Transcriptional Bursting Diversifies the Behaviour of a Toggle Switch: Hybrid Simulation of Stochastic Gene Expression

Hybrid models for gene expression combine stochastic and deterministic representations of the underlying biophysical mechanisms. According to one of the simplest hybrid formalisms, protein molecules are produced in randomly occurring bursts of a randomly distributed size while they are degraded dete...

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Veröffentlicht in:	Bulletin of mathematical biology 2013-02, Vol.75 (2), p.351-371
Hauptverfasser:	Bokes, Pavol, King, John R., Wood, Andrew T. A., Loose, Matthew
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Cell Biology Computer Simulation Gene Expression Regulation Life Sciences Mathematical and Computational Biology Mathematics Mathematics and Statistics Models, Genetic Original Article Stochastic Processes Transcription, Genetic
Online-Zugang:	Volltext
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