Developmental effects of plasticizer butyl benzyl phthalate after a single administration in rats

The objective of this study was to determine the susceptible day for the developmental toxicity of butyl benzyl phthalate (BBP) by a single administration on one of the days during organogenesis. Pregnant rats were given a single dose of BBP by gastric intubation at a dose of 1000 mg kg−1 on one of...

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Veröffentlicht in:	Journal of applied toxicology 1999-09, Vol.19 (5), p.357-365
Hauptverfasser:	Ema, Makoto, Miyawaki, Emiko, Kawashima, Kunio
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Body Weight - drug effects butyl benzyl phthalate developmental toxicity Embryo Loss - chemically induced embryolethality Embryology: invertebrates and vertebrates. Teratology Embryonic and Fetal Development - drug effects Female Fetus - abnormalities Fetus - drug effects foetal malformation Fundamental and applied biological sciences. Psychology Gestational Age Intubation, Gastrointestinal Male phthalic acid ester Phthalic Acids - toxicity Plasticizers - toxicity Pregnancy rat Rats Rats, Wistar teratogenicity Teratology. Teratogens Time Factors
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