CPAP therapy prevents increase in blood pressure after upper airway surgery for obstructive sleep apnoea
Objective The aim of this study was to investigate the efficacy of continuous positive airway pressure (CPAP) therapy following uvulopalatopharyngoplasty (UPPP) to prevent blood pressure (BP) elevation during sleep. Methods Sixteen normotensive patients with OSA were subjected to UPPP with or withou...
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| Veröffentlicht in: | Sleep & breathing 2013-12, Vol.17 (4), p.1289-1299 |
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| creator | de Araújo, Maria Teresa Martins Bissoli, Nazaré Sousa Gouvêa, Sônia Alves Pacheco, Maria Christina Thomé Meyer, Bernard Vasquez, Elizardo Corral Fleury, Bernard |
| description | Objective
The aim of this study was to investigate the efficacy of continuous positive airway pressure (CPAP) therapy following uvulopalatopharyngoplasty (UPPP) to prevent blood pressure (BP) elevation during sleep.
Methods
Sixteen normotensive patients with OSA were subjected to UPPP with or without septoplasty. These patients were instrumented for 24 h of ambulatory BP recording, polysomnography, nocturnal urinary catecholamine and pain evaluation using a visual analogue scale in the day prior to surgery (D−1), following the surgery (D+1) and 30 days later (D+30). For the D+1, the patients were divided into two groups: the without CPAP therapy group and the with CPAP therapy group.
Results
The apnoea–hypopnoea index (AHI) significantly increased in the patients without CPAP therapy compared with the D−1 (74 ± 23 vs. 35 ± 6 times/h,
p
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| doi_str_mv | 10.1007/s11325-013-0837-0 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1450186218</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1450186218</sourcerecordid><originalsourceid>FETCH-LOGICAL-c402t-5109704dd99356cb43f186fd847ddce221dd8ed9179ce144e341d24e4b54494b3</originalsourceid><addsrcrecordid>eNp1kU1P3DAQhi3UqlDoD-CCLFWVegl4bOfDR7Tql4QEBzhbjj2BoGwcPAlo_3293W2LKvVijzzPvDOel7FTEOcgRH1BAEqWhQBViEbVhThgR1BKWUAtzJtfsShMCfKQvSd6FAJ0Y-AdO5Sq0toIOGIPq5vLGz4_YHLThk8Jn3GcifejT-gIc8DbIcawTREtCbnrZkx8maZ8uj69uA3P7_eYNryLiceW5rT4uX9GTgPixN00RnQn7G3nBsIP-_uY3X39crv6Xlxdf_uxurwqvBZyLkoQphY6BGNUWflWqw6aqguNrkPwKCWE0GAwUBuPoDUqDUFq1G2Zf6Rbdcw-73SnFJ8WpNmue_I4DG7EuJAFXYqsKKHJ6Md_0Me4pDFPl6ksppuqVJmCHeVTJErY2Sn1a5c2FoTd2mB3Nthsg93aYEWuOdsrL-0aw5-K33vPwKc94Mi7oUtu9D395WpTSdlsObnjKKfGvORXI_63-0_CAZ9V</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1449448653</pqid></control><display><type>article</type><title>CPAP therapy prevents increase in blood pressure after upper airway surgery for obstructive sleep apnoea</title><source>MEDLINE</source><source>SpringerLink Journals - AutoHoldings</source><creator>de Araújo, Maria Teresa Martins ; Bissoli, Nazaré Sousa ; Gouvêa, Sônia Alves ; Pacheco, Maria Christina Thomé ; Meyer, Bernard ; Vasquez, Elizardo Corral ; Fleury, Bernard</creator><creatorcontrib>de Araújo, Maria Teresa Martins ; Bissoli, Nazaré Sousa ; Gouvêa, Sônia Alves ; Pacheco, Maria Christina Thomé ; Meyer, Bernard ; Vasquez, Elizardo Corral ; Fleury, Bernard</creatorcontrib><description>Objective
The aim of this study was to investigate the efficacy of continuous positive airway pressure (CPAP) therapy following uvulopalatopharyngoplasty (UPPP) to prevent blood pressure (BP) elevation during sleep.
Methods
Sixteen normotensive patients with OSA were subjected to UPPP with or without septoplasty. These patients were instrumented for 24 h of ambulatory BP recording, polysomnography, nocturnal urinary catecholamine and pain evaluation using a visual analogue scale in the day prior to surgery (D−1), following the surgery (D+1) and 30 days later (D+30). For the D+1, the patients were divided into two groups: the without CPAP therapy group and the with CPAP therapy group.
Results
The apnoea–hypopnoea index (AHI) significantly increased in the patients without CPAP therapy compared with the D−1 (74 ± 23 vs. 35 ± 6 times/h,
p
< 0.05), and in the CPAP group, there was a significant reduction in the average AHI value to 14 ± 6 times/h,
p
< 0.01. During D+1, we observed an increase in the nocturnal systolic BP (10 %), diastolic BP (12 %) and heart rate (14 %) in the group without CPAP. These metrics were re-established in the CPAP group to values that were similar to those that were observed on the D−1. The absence of nocturnal dipping in the group without CPAP was followed by a significant increase in nocturnal norepinephrine (42 ± 12 μg/l/12 h) and epinephrine (8 ± 2 μg/l/12 h) levels compared with the D−1 (norepinephrine 17 ± 3; epinephrine 2 ± 0.3 μg/l/12 h,
p
< 0.001). In the patients who used the CPAP treatment, the nocturnal catecholamine levels were similar to D−1. The effectiveness of intravenous analgesic therapy was verified by a significant decrease in the pain scores in patients both with and without CPAP therapy.
Conclusion
These data confirm an increase in the AHI on the night following UPPP with or without septoplasty. This increase promotes an absence of nocturnal dipping and a significant increase in urinary catecholamine levels. CPAP therapy was effective to prevent the transitory increase in BP.</description><identifier>ISSN: 1520-9512</identifier><identifier>EISSN: 1522-1709</identifier><identifier>DOI: 10.1007/s11325-013-0837-0</identifier><identifier>PMID: 23644901</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Adult ; Airway management ; Biological and medical sciences ; Blood pressure ; Blood Pressure - physiology ; Catecholamines - urine ; Cerebrospinal fluid. Meninges. Spinal cord ; Continuous Positive Airway Pressure ; Dentistry ; Disorders of higher nervous function. Focal brain diseases. Central vestibular syndrome and deafness. Brain stem syndromes ; Female ; Fundamental and applied biological sciences. Psychology ; Humans ; Hypertension - physiopathology ; Hypertension - prevention & control ; Internal Medicine ; Male ; Medical sciences ; Medicine ; Medicine & Public Health ; Middle Aged ; Nasal Septum - surgery ; Nervous system ; Nervous system (semeiology, syndromes) ; Neurology ; Original Article ; Otorhinolaryngology ; Pain Measurement ; Palate, Soft - surgery ; Pediatrics ; Pharynx - surgery ; Pneumology ; Pneumology/Respiratory System ; Polysomnography ; Postoperative Complications - physiopathology ; Postoperative Complications - prevention & control ; Respiratory system : syndromes and miscellaneous diseases ; Sleep apnea ; Sleep Apnea, Obstructive - physiopathology ; Sleep Apnea, Obstructive - surgery ; Sleep. Vigilance ; Surgical outcomes ; Sympathetic Nervous System - physiopathology ; Tonsillectomy ; Uvula - surgery ; Vertebrates: nervous system and sense organs</subject><ispartof>Sleep & breathing, 2013-12, Vol.17 (4), p.1289-1299</ispartof><rights>Springer-Verlag Berlin Heidelberg 2013</rights><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c402t-5109704dd99356cb43f186fd847ddce221dd8ed9179ce144e341d24e4b54494b3</citedby><cites>FETCH-LOGICAL-c402t-5109704dd99356cb43f186fd847ddce221dd8ed9179ce144e341d24e4b54494b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11325-013-0837-0$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11325-013-0837-0$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=27962281$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23644901$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>de Araújo, Maria Teresa Martins</creatorcontrib><creatorcontrib>Bissoli, Nazaré Sousa</creatorcontrib><creatorcontrib>Gouvêa, Sônia Alves</creatorcontrib><creatorcontrib>Pacheco, Maria Christina Thomé</creatorcontrib><creatorcontrib>Meyer, Bernard</creatorcontrib><creatorcontrib>Vasquez, Elizardo Corral</creatorcontrib><creatorcontrib>Fleury, Bernard</creatorcontrib><title>CPAP therapy prevents increase in blood pressure after upper airway surgery for obstructive sleep apnoea</title><title>Sleep & breathing</title><addtitle>Sleep Breath</addtitle><addtitle>Sleep Breath</addtitle><description>Objective
The aim of this study was to investigate the efficacy of continuous positive airway pressure (CPAP) therapy following uvulopalatopharyngoplasty (UPPP) to prevent blood pressure (BP) elevation during sleep.
Methods
Sixteen normotensive patients with OSA were subjected to UPPP with or without septoplasty. These patients were instrumented for 24 h of ambulatory BP recording, polysomnography, nocturnal urinary catecholamine and pain evaluation using a visual analogue scale in the day prior to surgery (D−1), following the surgery (D+1) and 30 days later (D+30). For the D+1, the patients were divided into two groups: the without CPAP therapy group and the with CPAP therapy group.
Results
The apnoea–hypopnoea index (AHI) significantly increased in the patients without CPAP therapy compared with the D−1 (74 ± 23 vs. 35 ± 6 times/h,
p
< 0.05), and in the CPAP group, there was a significant reduction in the average AHI value to 14 ± 6 times/h,
p
< 0.01. During D+1, we observed an increase in the nocturnal systolic BP (10 %), diastolic BP (12 %) and heart rate (14 %) in the group without CPAP. These metrics were re-established in the CPAP group to values that were similar to those that were observed on the D−1. The absence of nocturnal dipping in the group without CPAP was followed by a significant increase in nocturnal norepinephrine (42 ± 12 μg/l/12 h) and epinephrine (8 ± 2 μg/l/12 h) levels compared with the D−1 (norepinephrine 17 ± 3; epinephrine 2 ± 0.3 μg/l/12 h,
p
< 0.001). In the patients who used the CPAP treatment, the nocturnal catecholamine levels were similar to D−1. The effectiveness of intravenous analgesic therapy was verified by a significant decrease in the pain scores in patients both with and without CPAP therapy.
Conclusion
These data confirm an increase in the AHI on the night following UPPP with or without septoplasty. This increase promotes an absence of nocturnal dipping and a significant increase in urinary catecholamine levels. CPAP therapy was effective to prevent the transitory increase in BP.</description><subject>Adult</subject><subject>Airway management</subject><subject>Biological and medical sciences</subject><subject>Blood pressure</subject><subject>Blood Pressure - physiology</subject><subject>Catecholamines - urine</subject><subject>Cerebrospinal fluid. Meninges. Spinal cord</subject><subject>Continuous Positive Airway Pressure</subject><subject>Dentistry</subject><subject>Disorders of higher nervous function. Focal brain diseases. Central vestibular syndrome and deafness. Brain stem syndromes</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Humans</subject><subject>Hypertension - physiopathology</subject><subject>Hypertension - prevention & control</subject><subject>Internal Medicine</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Nasal Septum - surgery</subject><subject>Nervous system</subject><subject>Nervous system (semeiology, syndromes)</subject><subject>Neurology</subject><subject>Original Article</subject><subject>Otorhinolaryngology</subject><subject>Pain Measurement</subject><subject>Palate, Soft - surgery</subject><subject>Pediatrics</subject><subject>Pharynx - surgery</subject><subject>Pneumology</subject><subject>Pneumology/Respiratory System</subject><subject>Polysomnography</subject><subject>Postoperative Complications - physiopathology</subject><subject>Postoperative Complications - prevention & control</subject><subject>Respiratory system : syndromes and miscellaneous diseases</subject><subject>Sleep apnea</subject><subject>Sleep Apnea, Obstructive - physiopathology</subject><subject>Sleep Apnea, Obstructive - surgery</subject><subject>Sleep. Vigilance</subject><subject>Surgical outcomes</subject><subject>Sympathetic Nervous System - physiopathology</subject><subject>Tonsillectomy</subject><subject>Uvula - surgery</subject><subject>Vertebrates: nervous system and sense organs</subject><issn>1520-9512</issn><issn>1522-1709</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp1kU1P3DAQhi3UqlDoD-CCLFWVegl4bOfDR7Tql4QEBzhbjj2BoGwcPAlo_3293W2LKvVijzzPvDOel7FTEOcgRH1BAEqWhQBViEbVhThgR1BKWUAtzJtfsShMCfKQvSd6FAJ0Y-AdO5Sq0toIOGIPq5vLGz4_YHLThk8Jn3GcifejT-gIc8DbIcawTREtCbnrZkx8maZ8uj69uA3P7_eYNryLiceW5rT4uX9GTgPixN00RnQn7G3nBsIP-_uY3X39crv6Xlxdf_uxurwqvBZyLkoQphY6BGNUWflWqw6aqguNrkPwKCWE0GAwUBuPoDUqDUFq1G2Zf6Rbdcw-73SnFJ8WpNmue_I4DG7EuJAFXYqsKKHJ6Md_0Me4pDFPl6ksppuqVJmCHeVTJErY2Sn1a5c2FoTd2mB3Nthsg93aYEWuOdsrL-0aw5-K33vPwKc94Mi7oUtu9D395WpTSdlsObnjKKfGvORXI_63-0_CAZ9V</recordid><startdate>20131201</startdate><enddate>20131201</enddate><creator>de Araújo, Maria Teresa Martins</creator><creator>Bissoli, Nazaré Sousa</creator><creator>Gouvêa, Sônia Alves</creator><creator>Pacheco, Maria Christina Thomé</creator><creator>Meyer, Bernard</creator><creator>Vasquez, Elizardo Corral</creator><creator>Fleury, Bernard</creator><general>Springer Berlin Heidelberg</general><general>Springer</general><general>Springer Nature B.V</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0-V</scope><scope>3V.</scope><scope>7T5</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>88J</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M2R</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20131201</creationdate><title>CPAP therapy prevents increase in blood pressure after upper airway surgery for obstructive sleep apnoea</title><author>de Araújo, Maria Teresa Martins ; Bissoli, Nazaré Sousa ; Gouvêa, Sônia Alves ; Pacheco, Maria Christina Thomé ; Meyer, Bernard ; Vasquez, Elizardo Corral ; Fleury, Bernard</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c402t-5109704dd99356cb43f186fd847ddce221dd8ed9179ce144e341d24e4b54494b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Adult</topic><topic>Airway management</topic><topic>Biological and medical sciences</topic><topic>Blood pressure</topic><topic>Blood Pressure - physiology</topic><topic>Catecholamines - urine</topic><topic>Cerebrospinal fluid. Meninges. Spinal cord</topic><topic>Continuous Positive Airway Pressure</topic><topic>Dentistry</topic><topic>Disorders of higher nervous function. Focal brain diseases. Central vestibular syndrome and deafness. Brain stem syndromes</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Humans</topic><topic>Hypertension - physiopathology</topic><topic>Hypertension - prevention & control</topic><topic>Internal Medicine</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Nasal Septum - surgery</topic><topic>Nervous system</topic><topic>Nervous system (semeiology, syndromes)</topic><topic>Neurology</topic><topic>Original Article</topic><topic>Otorhinolaryngology</topic><topic>Pain Measurement</topic><topic>Palate, Soft - surgery</topic><topic>Pediatrics</topic><topic>Pharynx - surgery</topic><topic>Pneumology</topic><topic>Pneumology/Respiratory System</topic><topic>Polysomnography</topic><topic>Postoperative Complications - physiopathology</topic><topic>Postoperative Complications - prevention & control</topic><topic>Respiratory system : syndromes and miscellaneous diseases</topic><topic>Sleep apnea</topic><topic>Sleep Apnea, Obstructive - physiopathology</topic><topic>Sleep Apnea, Obstructive - surgery</topic><topic>Sleep. Vigilance</topic><topic>Surgical outcomes</topic><topic>Sympathetic Nervous System - physiopathology</topic><topic>Tonsillectomy</topic><topic>Uvula - surgery</topic><topic>Vertebrates: nervous system and sense organs</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>de Araújo, Maria Teresa Martins</creatorcontrib><creatorcontrib>Bissoli, Nazaré Sousa</creatorcontrib><creatorcontrib>Gouvêa, Sônia Alves</creatorcontrib><creatorcontrib>Pacheco, Maria Christina Thomé</creatorcontrib><creatorcontrib>Meyer, Bernard</creatorcontrib><creatorcontrib>Vasquez, Elizardo Corral</creatorcontrib><creatorcontrib>Fleury, Bernard</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Social Sciences Premium Collection</collection><collection>ProQuest Central (Corporate)</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Social Science Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Social Science Premium Collection</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest Psychology</collection><collection>Social Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Sleep & breathing</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>de Araújo, Maria Teresa Martins</au><au>Bissoli, Nazaré Sousa</au><au>Gouvêa, Sônia Alves</au><au>Pacheco, Maria Christina Thomé</au><au>Meyer, Bernard</au><au>Vasquez, Elizardo Corral</au><au>Fleury, Bernard</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>CPAP therapy prevents increase in blood pressure after upper airway surgery for obstructive sleep apnoea</atitle><jtitle>Sleep & breathing</jtitle><stitle>Sleep Breath</stitle><addtitle>Sleep Breath</addtitle><date>2013-12-01</date><risdate>2013</risdate><volume>17</volume><issue>4</issue><spage>1289</spage><epage>1299</epage><pages>1289-1299</pages><issn>1520-9512</issn><eissn>1522-1709</eissn><abstract>Objective
The aim of this study was to investigate the efficacy of continuous positive airway pressure (CPAP) therapy following uvulopalatopharyngoplasty (UPPP) to prevent blood pressure (BP) elevation during sleep.
Methods
Sixteen normotensive patients with OSA were subjected to UPPP with or without septoplasty. These patients were instrumented for 24 h of ambulatory BP recording, polysomnography, nocturnal urinary catecholamine and pain evaluation using a visual analogue scale in the day prior to surgery (D−1), following the surgery (D+1) and 30 days later (D+30). For the D+1, the patients were divided into two groups: the without CPAP therapy group and the with CPAP therapy group.
Results
The apnoea–hypopnoea index (AHI) significantly increased in the patients without CPAP therapy compared with the D−1 (74 ± 23 vs. 35 ± 6 times/h,
p
< 0.05), and in the CPAP group, there was a significant reduction in the average AHI value to 14 ± 6 times/h,
p
< 0.01. During D+1, we observed an increase in the nocturnal systolic BP (10 %), diastolic BP (12 %) and heart rate (14 %) in the group without CPAP. These metrics were re-established in the CPAP group to values that were similar to those that were observed on the D−1. The absence of nocturnal dipping in the group without CPAP was followed by a significant increase in nocturnal norepinephrine (42 ± 12 μg/l/12 h) and epinephrine (8 ± 2 μg/l/12 h) levels compared with the D−1 (norepinephrine 17 ± 3; epinephrine 2 ± 0.3 μg/l/12 h,
p
< 0.001). In the patients who used the CPAP treatment, the nocturnal catecholamine levels were similar to D−1. The effectiveness of intravenous analgesic therapy was verified by a significant decrease in the pain scores in patients both with and without CPAP therapy.
Conclusion
These data confirm an increase in the AHI on the night following UPPP with or without septoplasty. This increase promotes an absence of nocturnal dipping and a significant increase in urinary catecholamine levels. CPAP therapy was effective to prevent the transitory increase in BP.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>23644901</pmid><doi>10.1007/s11325-013-0837-0</doi><tpages>11</tpages></addata></record> |
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| identifier | ISSN: 1520-9512 |
| ispartof | Sleep & breathing, 2013-12, Vol.17 (4), p.1289-1299 |
| issn | 1520-9512 1522-1709 |
| language | eng |
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| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Adult Airway management Biological and medical sciences Blood pressure Blood Pressure - physiology Catecholamines - urine Cerebrospinal fluid. Meninges. Spinal cord Continuous Positive Airway Pressure Dentistry Disorders of higher nervous function. Focal brain diseases. Central vestibular syndrome and deafness. Brain stem syndromes Female Fundamental and applied biological sciences. Psychology Humans Hypertension - physiopathology Hypertension - prevention & control Internal Medicine Male Medical sciences Medicine Medicine & Public Health Middle Aged Nasal Septum - surgery Nervous system Nervous system (semeiology, syndromes) Neurology Original Article Otorhinolaryngology Pain Measurement Palate, Soft - surgery Pediatrics Pharynx - surgery Pneumology Pneumology/Respiratory System Polysomnography Postoperative Complications - physiopathology Postoperative Complications - prevention & control Respiratory system : syndromes and miscellaneous diseases Sleep apnea Sleep Apnea, Obstructive - physiopathology Sleep Apnea, Obstructive - surgery Sleep. Vigilance Surgical outcomes Sympathetic Nervous System - physiopathology Tonsillectomy Uvula - surgery Vertebrates: nervous system and sense organs |
| title | CPAP therapy prevents increase in blood pressure after upper airway surgery for obstructive sleep apnoea |
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