Direct AT2 receptor stimulation is athero-protective and stabilizes plaque in Apolipoprotein E-deficient mice

Abstract Background The angiotensin II type 2 receptor (AT2 R) has been suggested to have an athero-protective role, however no studies have investigated the effect of direct stimulation of this receptor in atherosclerosis. Thus this study aimed to determine the effect of direct AT2 R stimulation in...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	International journal of cardiology 2013-11, Vol.169 (4), p.281-287
Hauptverfasser:	Kljajic, Sonja Tesanovic, Widdop, Robert E, Vinh, Antony, Welungoda, Iresha, Bosnyak, Sanja, Jones, Emma S, Gaspari, Tracey A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apolipoproteins E - deficiency AT2 receptor Atherosclerosis Atherosclerosis (general aspects, experimental research) Atherosclerosis - drug therapy Atherosclerosis - metabolism Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Cardiotonic Agents - pharmacology Cardiotonic Agents - therapeutic use Cardiovascular CGP42112 Cohort Studies Endothelial dysfunction Heart Male Medical sciences Mice Mice, Inbred C57BL Mice, Knockout Oligopeptides - pharmacology Oligopeptides - therapeutic use Plaque rupture Plaque, Atherosclerotic - drug therapy Plaque, Atherosclerotic - metabolism Receptor, Angiotensin, Type 2 - agonists Receptor, Angiotensin, Type 2 - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!