Mast Cell Tryptase Induces Eosinophil Recruitment in the Pleural Cavity of Mice via Proteinase-Activated Receptor 2

Proteinase-activated receptor (PAR) 2 has been implicated in eosinophil migration. Mast cell (MC) tryptase has been similarly implicated in allergic diseases through the activation of PAR-2, but the role of this receptor in MC tryptase-induced inflammation is not well elucidated. This study aims to...

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Veröffentlicht in:	Inflammation 2013-12, Vol.36 (6), p.1260-1267
Hauptverfasser:	Matos, Natália A., Silva, Josiane F., Matsui, Tamires C., Damasceno, Karine A., Duarte, Igor D. G., Lemos, Virginia S., Cassali, Geovanni D., Klein, André
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomedical and Life Sciences Biomedicine Cell Movement - immunology Dipeptides - pharmacology Eosinophils - immunology Immunology Inflammation - immunology Internal Medicine Male Mice Mice, Inbred BALB C Oligopeptides - immunology Oligopeptides - pharmacology Pathology Pharmacology/Toxicology Piperazines - pharmacology Pleural Cavity - immunology Pleurisy - immunology Receptor, PAR-2 - immunology Rheumatology Tryptases - immunology
Online-Zugang:	Volltext
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