A Novel Approach for Developing and Interpreting Treatment Moderator Profiles in Randomized Clinical Trials

IMPORTANCE Identifying treatment moderators may help mental health practitioners arrive at more precise treatment selection for individual patients and can focus clinical research on subpopulations that differ in treatment response. OBJECTIVE To demonstrate a novel exploratory approach to moderation...

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Veröffentlicht in:	JAMA psychiatry (Chicago, Ill.) Ill.), 2013-11, Vol.70 (11), p.1241-1247
Hauptverfasser:	Wallace, Meredith L, Frank, Ellen, Kraemer, Helena C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Clinical trials Effect Modifier, Epidemiologic Female Humans Male Medical sciences Mental depression Mental health care Models, Statistical Patient Selection Precision Medicine - methods Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychotherapy Randomized Controlled Trials as Topic - methods
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