Long Interspersed Nucleotide Element 1 Hypomethylation Is Associated With Poor Prognosis of Lung Adenocarcinoma

Background Genome-wide DNA hypomethylation is known to play important roles in genomic instability and carcinogenesis. Methylation in long interspersed nucleotide element 1 (LINE-1) is a good indicator of the global DNA methylation level within a cell. The aim of this study was to evaluate prognosti...

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Veröffentlicht in:	The Annals of thoracic surgery 2013-11, Vol.96 (5), p.1790-1794
Hauptverfasser:	Ikeda, Koei, MD, PhD, Shiraishi, Kenji, MD, PhD, Eguchi, Ayami, MT, Shibata, Hidekatsu, MD, PhD, Yoshimoto, Kentaro, MD, PhD, Mori, Takeshi, MD, PhD, Baba, Yoshifumi, MD, PhD, Baba, Hideo, MD, PhD, Suzuki, Makoto, MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - genetics Adenocarcinoma of Lung Aged Cardiothoracic Surgery DNA Methylation Female Humans Long Interspersed Nucleotide Elements Lung Neoplasms - genetics Male Prognosis Surgery
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