Exploratory geographical analysis of hypoxic subvolumes using 18F-MISO-PET imaging in patients with head and neck cancer in the course of primary chemoradiotherapy

Hypoxia in head and neck tumours is associated with poor prognosis and outcome, and can be visualized using 18F-MISO-PET imaging; however, it is not clear whether the size and location of hypoxic subvolumes remain stable during therapy. In a pilot project, we conducted an exploratory analysis of per...

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Veröffentlicht in:	Radiotherapy and oncology 2013-09, Vol.108 (3), p.511-516
Hauptverfasser:	Bittner, Martin-Immanuel, Wiedenmann, Nicole, Bucher, Sabine, Hentschel, Michael, Mix, Michael, Weber, Wolfgang A., Grosu, Anca-Ligia
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological imaging Cell Hypoxia Chemoradiotherapy Female Fluorine Radioisotopes Head and Neck Neoplasms - diagnostic imaging Head and Neck Neoplasms - pathology Head and Neck Neoplasms - therapy Head and neck tumours Humans Hypoxia imaging Male Misonidazole - analogs & derivatives PET Pilot Projects Positron-Emission Tomography - methods Radiopharmaceuticals Tumour hypoxia
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