Synthesis and in vitro/in vivo antibacterial activity of oxazolidinones having thiocarbamate at C-5 on the A-ring and an amide- or urea-substituted [1,2,5]triazepane or [1,2,5]oxadiazepane as the C-ring

Oxazolidinones bearing a seven-membered [1,2,5]triazepane or [1,2,5]oxadiazepane heterocycle substituted with an amide or urea functionality as the C-ring and having a [1,2,3]triazole, a thiocarbamate, an isoxazole-3-ylamino, or a thioacetamide C-5 side chain unit on the A-ring instead of the typica...

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Veröffentlicht in:European journal of medicinal chemistry 2013-11, Vol.69, p.262-277
Hauptverfasser: Suzuki, Hideyuki, Utsunomiya, Iwao, Shudo, Koichi, Fukuhara, Norio, Iwaki, Tsutomu, Yasukata, Tatsuro
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Sprache:eng
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