The components of taurine transport across the rat small intestine A kinetic study

The transport of taurine across adult Sprague-Dawley rat small intestine was studied in vitro using small intestinal strips. The kinetics of the transport mechanism were investigated under both steady-state and influx conditions. Our findings were compatible with the presence of two distinct transpo...

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Veröffentlicht in:	Amino acids 1993-02, Vol.5 (1), p.77-89
Hauptverfasser:	Sharafuddin, M J, Nassar, C F
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Sprache:	eng
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description	The transport of taurine across adult Sprague-Dawley rat small intestine was studied in vitro using small intestinal strips. The kinetics of the transport mechanism were investigated under both steady-state and influx conditions. Our findings were compatible with the presence of two distinct transport mechanisms; a linear non-carrier mediated component and a saturable carrier mediated component, with almost equal contribution from each. The mediated component was found to be largely Na(+)-dependent and exhibited marked inhibition by B-alanine and structurally related sulfur amino acids.
doi_str_mv	10.1007/BF00806194
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title	The components of taurine transport across the rat small intestine A kinetic study
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