Novel and cost-effective 6-plex isobaric tagging reagent, DiART, is effective for identification and relative quantification of complex protein mixtures using PQD fragmentation

Deuterium isobaric Amine Reactive Tag (DiART) reagents facilitate relative quantification during proteomic analysis in a functionally similar manner to commercially available isobaric tag for relative and absolute quantitation (iTRAQ) and tandem mass tag (TMT) reagents. In contrast to iTRAQ and TMT,...

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Veröffentlicht in:Journal of mass spectrometry. 2013-09, Vol.48 (9), p.1032-1041
Hauptverfasser: Ramsubramaniam, Nikhil, Tao, Feng, Li, Shuwei, Marten, Mark R.
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Sprache:eng
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