Modulation of murine gastric vagal afferent mechanosensitivity by neuropeptide W

Aim Neuropeptide W (NPW) is an endogenous ligand for the receptors GPR7 and GPR8 and is involved in central regulation of energy homeostasis. NPW in the periphery is found in gastric gastrin (G) cells. In the stomach, energy intake is influenced by vagal afferent signals, so we aimed to determine th...

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Veröffentlicht in:	Acta Physiologica 2013-10, Vol.209 (2), p.179-191
Hauptverfasser:	Li, H., Kentish, S. J., Kritas, S., Young, R. L., Isaacs, N. J., O'Donnell, T. A., Blackshaw, L. A., Wittert, G. A., Page, A. J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Afferent Pathways - metabolism Animals Eating - physiology Female food restriction Gastric Mucosa - metabolism high-fat diet Immunohistochemistry Mice Mice, Inbred C57BL neuropeptide W Neuropeptides - metabolism Real-Time Polymerase Chain Reaction Receptors, G-Protein-Coupled - metabolism Receptors, Neuropeptide - metabolism Reverse Transcriptase Polymerase Chain Reaction Stomach - innervation Stomach - metabolism Stress, Mechanical vagal afferents Vagus Nerve - metabolism
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