Circulatory Shock
Circulatory shock is present when physical signs and changes in laboratory values suggest tissue hypoperfusion. This article in the Critical Care Medicine series reviews the diagnosis and treatment of various forms of shock. Shock is the clinical expression of circulatory failure that results in ina...
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Veröffentlicht in: | The New England journal of medicine 2013-10, Vol.369 (18), p.1726-1734 |
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creator | Vincent, Jean-Louis De Backer, Daniel |
description | Circulatory shock is present when physical signs and changes in laboratory values suggest tissue hypoperfusion. This article in the Critical Care Medicine series reviews the diagnosis and treatment of various forms of shock.
Shock is the clinical expression of circulatory failure that results in inadequate cellular oxygen utilization. Shock is a common condition in critical care, affecting about one third of patients in the intensive care unit (ICU).
1
A diagnosis of shock is based on clinical, hemodynamic, and biochemical signs, which can broadly be summarized into three components. First, systemic arterial hypotension is usually present, but the magnitude of the hypotension may be only moderate, especially in patients with chronic hypertension. Typically, in adults, the systolic arterial pressure is less than 90 mm Hg or the mean arterial pressure is less than 70 . . . |
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Shock is the clinical expression of circulatory failure that results in inadequate cellular oxygen utilization. Shock is a common condition in critical care, affecting about one third of patients in the intensive care unit (ICU).
1
A diagnosis of shock is based on clinical, hemodynamic, and biochemical signs, which can broadly be summarized into three components. First, systemic arterial hypotension is usually present, but the magnitude of the hypotension may be only moderate, especially in patients with chronic hypertension. Typically, in adults, the systolic arterial pressure is less than 90 mm Hg or the mean arterial pressure is less than 70 . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJMra1208943</identifier><identifier>PMID: 24171518</identifier><identifier>CODEN: NEJMAG</identifier><language>eng</language><publisher>Waltham, MA: Massachusetts Medical Society</publisher><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Biological and medical sciences ; Cardiotonic Agents - therapeutic use ; Cardiovascular Agents - therapeutic use ; Catheters ; Diagnosis, Differential ; Embolisms ; Emergency and intensive cardiocirculatory care. Cardiogenic shock. Coronary intensive care ; Fluid Therapy ; Heart attacks ; Humans ; Intensive care medicine ; Lactic Acid - blood ; Medical diagnosis ; Medical sciences ; Medical treatment ; Patients ; Shock - diagnosis ; Shock - drug therapy ; Shock - therapy ; Vasoconstrictor Agents - therapeutic use ; Vasodilator Agents - therapeutic use</subject><ispartof>The New England journal of medicine, 2013-10, Vol.369 (18), p.1726-1734</ispartof><rights>Copyright © 2013 Massachusetts Medical Society. All rights reserved.</rights><rights>2014 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c464t-f917852f46aee00f356c18dfe865c54ebf16b6f81d459a325cd4af19084382ca3</citedby><cites>FETCH-LOGICAL-c464t-f917852f46aee00f356c18dfe865c54ebf16b6f81d459a325cd4af19084382ca3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJMra1208943$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/1447633596?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>315,782,786,2763,2764,26112,27933,27934,52391,54073,64394,64396,64398,72478</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=27816489$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24171518$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Vincent, Jean-Louis</contributor><contributor>Finfer, Simon R</contributor><contributor>Finfer, Simon R.</contributor><creatorcontrib>Vincent, Jean-Louis</creatorcontrib><creatorcontrib>De Backer, Daniel</creatorcontrib><title>Circulatory Shock</title><title>The New England journal of medicine</title><addtitle>N Engl J Med</addtitle><description>Circulatory shock is present when physical signs and changes in laboratory values suggest tissue hypoperfusion. This article in the Critical Care Medicine series reviews the diagnosis and treatment of various forms of shock.
Shock is the clinical expression of circulatory failure that results in inadequate cellular oxygen utilization. Shock is a common condition in critical care, affecting about one third of patients in the intensive care unit (ICU).
1
A diagnosis of shock is based on clinical, hemodynamic, and biochemical signs, which can broadly be summarized into three components. First, systemic arterial hypotension is usually present, but the magnitude of the hypotension may be only moderate, especially in patients with chronic hypertension. Typically, in adults, the systolic arterial pressure is less than 90 mm Hg or the mean arterial pressure is less than 70 . . .</description><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Biological and medical sciences</subject><subject>Cardiotonic Agents - therapeutic use</subject><subject>Cardiovascular Agents - therapeutic use</subject><subject>Catheters</subject><subject>Diagnosis, Differential</subject><subject>Embolisms</subject><subject>Emergency and intensive cardiocirculatory care. Cardiogenic shock. Coronary intensive care</subject><subject>Fluid Therapy</subject><subject>Heart attacks</subject><subject>Humans</subject><subject>Intensive care medicine</subject><subject>Lactic Acid - blood</subject><subject>Medical diagnosis</subject><subject>Medical sciences</subject><subject>Medical treatment</subject><subject>Patients</subject><subject>Shock - diagnosis</subject><subject>Shock - drug therapy</subject><subject>Shock - therapy</subject><subject>Vasoconstrictor Agents - therapeutic use</subject><subject>Vasodilator Agents - therapeutic use</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp10E1LAzEQBuAgiq3VgwevIojgZTWTTLLJsZT6RdWDel7SbIJb96Mm3UP_vVtaLQrOZS4P7wwvISdAr4AKef00fngMBhhVGvkO6YPgPEGkcpf0KWUqwVTzHjmIcUa7AdT7pMcQUhCg-uR4VATblmbRhOXZy3tjPw7JnjdldEebPSBvN-PX0V0yeb69Hw0niUWJi8RrSJVgHqVxjlLPhbSgcu-UFFagm3qQU-kV5Ci04UzYHI0HTRVyxazhA3K5zp2H5rN1cZFVRbSuLE3tmjZmgKgY7a6kHT3_Q2dNG-ruu5VKJedCy04la2VDE2NwPpuHojJhmQHNVl1lv7rq_OkmtZ1WLv_R3-V04GIDTLSm9MHUtohblyqQqPTWVVXMajer_jn4BXCYeSs</recordid><startdate>20131031</startdate><enddate>20131031</enddate><creator>Vincent, Jean-Louis</creator><creator>De Backer, Daniel</creator><general>Massachusetts Medical Society</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0TZ</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K0Y</scope><scope>LK8</scope><scope>M0R</scope><scope>M0T</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2P</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20131031</creationdate><title>Circulatory Shock</title><author>Vincent, Jean-Louis ; De Backer, Daniel</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c464t-f917852f46aee00f356c18dfe865c54ebf16b6f81d459a325cd4af19084382ca3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Biological and medical sciences</topic><topic>Cardiotonic Agents - therapeutic use</topic><topic>Cardiovascular Agents - therapeutic use</topic><topic>Catheters</topic><topic>Diagnosis, Differential</topic><topic>Embolisms</topic><topic>Emergency and intensive cardiocirculatory care. Cardiogenic shock. Coronary intensive care</topic><topic>Fluid Therapy</topic><topic>Heart attacks</topic><topic>Humans</topic><topic>Intensive care medicine</topic><topic>Lactic Acid - blood</topic><topic>Medical diagnosis</topic><topic>Medical sciences</topic><topic>Medical treatment</topic><topic>Patients</topic><topic>Shock - diagnosis</topic><topic>Shock - drug therapy</topic><topic>Shock - therapy</topic><topic>Vasoconstrictor Agents - therapeutic use</topic><topic>Vasodilator Agents - therapeutic use</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Vincent, Jean-Louis</creatorcontrib><creatorcontrib>De Backer, Daniel</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Pharma and Biotech Premium PRO</collection><collection>ProQuest Nursing and Allied Health Journals</collection><collection>ProQuest Health and Medical</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>eLibrary</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>New England Journal of Medicine</collection><collection>ProQuest Biological Science Collection</collection><collection>Consumer Health Database</collection><collection>ProQuest Health Management</collection><collection>Medical Database</collection><collection>ProQuest Psychology Journals</collection><collection>ProQuest Research Library</collection><collection>ProQuest Science Journals</collection><collection>ProQuest Biological Science Journals</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>The New England journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Vincent, Jean-Louis</au><au>De Backer, Daniel</au><au>Vincent, Jean-Louis</au><au>Finfer, Simon R</au><au>Finfer, Simon R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Circulatory Shock</atitle><jtitle>The New England journal of medicine</jtitle><addtitle>N Engl J Med</addtitle><date>2013-10-31</date><risdate>2013</risdate><volume>369</volume><issue>18</issue><spage>1726</spage><epage>1734</epage><pages>1726-1734</pages><issn>0028-4793</issn><eissn>1533-4406</eissn><coden>NEJMAG</coden><abstract>Circulatory shock is present when physical signs and changes in laboratory values suggest tissue hypoperfusion. This article in the Critical Care Medicine series reviews the diagnosis and treatment of various forms of shock.
Shock is the clinical expression of circulatory failure that results in inadequate cellular oxygen utilization. Shock is a common condition in critical care, affecting about one third of patients in the intensive care unit (ICU).
1
A diagnosis of shock is based on clinical, hemodynamic, and biochemical signs, which can broadly be summarized into three components. First, systemic arterial hypotension is usually present, but the magnitude of the hypotension may be only moderate, especially in patients with chronic hypertension. Typically, in adults, the systolic arterial pressure is less than 90 mm Hg or the mean arterial pressure is less than 70 . . .</abstract><cop>Waltham, MA</cop><pub>Massachusetts Medical Society</pub><pmid>24171518</pmid><doi>10.1056/NEJMra1208943</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Cardiotonic Agents - therapeutic use Cardiovascular Agents - therapeutic use Catheters Diagnosis, Differential Embolisms Emergency and intensive cardiocirculatory care. Cardiogenic shock. Coronary intensive care Fluid Therapy Heart attacks Humans Intensive care medicine Lactic Acid - blood Medical diagnosis Medical sciences Medical treatment Patients Shock - diagnosis Shock - drug therapy Shock - therapy Vasoconstrictor Agents - therapeutic use Vasodilator Agents - therapeutic use |
title | Circulatory Shock |
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