Chromosomal profiles of high-grade cervical intraepithelial neoplasia relate to duration of preceding high-risk human papillomavirus infection

High‐grade cervical intraepithelial neoplasia (CIN2/3) represents a heterogeneous disease both with respect to clinical behavior and chromosomal aberrations detected. We hypothesized that the extent of chromosomal aberrations reflects the duration of their existence. Chromosomal profiles were determ...

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Veröffentlicht in:	International journal of cancer 2012-08, Vol.131 (4), p.E579-E585
Hauptverfasser:	Bierkens, Mariska, Wilting, Saskia M., van Wieringen, Wessel N., van Kemenade, Folkert J., Bleeker, Maaike C.G., Jordanova, Ekaterina S., Bekker-Lettink, Marjolein, van de Wiel, Mark A., Ylstra, Bauke, Meijer, Chris J.L.M., Snijders, Peter J.F., Steenbergen, Renske D.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alphapapillomavirus - isolation & purification arrayCGH Cancer Carcinoma, Squamous Cell - genetics Carcinoma, Squamous Cell - virology Cervical cancer Cervical Intraepithelial Neoplasia - genetics Cervical Intraepithelial Neoplasia - virology Chromosome Aberrations Chromosomes Comparative Genomic Hybridization Female high-grade cervical intraepithelial neoplasia HPV Human papillomavirus Humans Medical research Papillomavirus Infections - complications Papillomavirus Infections - virology Risk factors
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