A novel method for increasing bacterial cellular yields of a fimbrial subunit polypeptide

An in‐depth understanding of the genetic organisation of the K88 adhesion fimbriae determinant has been used to construct novel recombinant plasmids which direct the expression of high levels of K88 fimbriae suitable for use in vaccine preparations when harboured by Escherichia coli K12. This was ac...

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Veröffentlicht in:	FEMS microbiology letters 1985-01, Vol.28 (2), p.193-197
Hauptverfasser:	Winther, Michael D., Pickard, Derek, Dougan, Gordon
Format:	Artikel
Sprache:	eng
Schlagworte:	antigens Bacteriology Biological and medical sciences cloning vectors Escherichia coli Fimbrial subunit gene Fundamental and applied biological sciences. Psychology gene cloning genes Genetics increased yields K88 Microbiology pili vaccines
Online-Zugang:	Volltext
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