Standardization of LC-MS for therapeutic drug monitoring of tacrolimus

LC-MS is increasingly used for therapeutic drug monitoring of tacrolimus. A recent summary from an international proficiency-testing scheme demonstrated that the mass spectrometry respondents were the largest method group. However, these methods lack standardization, which may explain the relatively...

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Veröffentlicht in:	Clinical chemistry (Baltimore, Md.) Md.), 2013-11, Vol.59 (11), p.1630-1637
Hauptverfasser:	Annesley, Thomas M, McKeown, Denise A, Holt, David W, Mussell, Christopher, Champarnaud, Elodie, Harter, Leonie, Calton, Lisa J, Mason, Donald S
Format:	Artikel
Sprache:	eng
Schlagworte:	Accuracy Agreements Architects Blood Calibration Chromatography Chromatography, Liquid - standards Clinical medicine Drug Monitoring - methods Humans Immunoassay Immunosuppressive Agents - standards Immunosuppressive Agents - therapeutic use Laboratories Laboratory Proficiency Testing Mass spectrometry Methods Reference Standards Standardization Studies Tacrolimus - standards Tacrolimus - therapeutic use Tandem Mass Spectrometry - standards
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