Holothuria grisea agglutinin (HGA): the first invertebrate lectin with anti-inflammatory effects

Holothuria grisea agglutinin (HGA) is a dimeric lectin of molecular mass 228 kDa by gel filtration with monomers of 105 kDa by SDS‐PAGE. The lectin is highly thermostable as it retains full activity for 1 h at 70 °C. Unlike other lectins purified from marine invertebrates, the hemagglutination activ...

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Veröffentlicht in:	Fundamental & clinical pharmacology 2013-12, Vol.27 (6), p.656-668
Hauptverfasser:	Moura, Raniere da M., Aragão, Karoline S., de Melo, Arthur A., Carneiro, Rômulo F., Osório, César B. H., Luz, Patricia B., de Queiroz, Alexandre F. S., dos Santos, Elizeu A., de Alencar, Nylane M. N., Cavada, Benildo S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Agglutinins - isolation & purification Agglutinins - pharmacology Animals anti-inflammatory Anti-Inflammatory Agents - administration & dosage Anti-Inflammatory Agents - isolation & purification Anti-Inflammatory Agents - pharmacology antinociceptive Behavior, Animal - drug effects Biological and medical sciences Carrageenan - toxicity Disease Models, Animal Dose-Response Relationship, Drug echinoderm Hemagglutination Inhibition Tests Holothuria - chemistry Holothuria grisea Humans Inflammation - drug therapy Inflammation - pathology lectin Lectins - administration & dosage Lectins - isolation & purification Lectins - pharmacology Male Medical sciences Pain Measurement Pharmacology. Drug treatments Rats Rats, Wistar
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