Effect of location of out-of-hospital cardiac arrest on survival outcomes
This study aims to study how the effect of the location of patient collapses from cardiac arrest, in the residential and non-residential areas within Singapore, relates to certain survival outcomes. A retrospective cohort study of data were done from the Cardiac Arrest and Resuscitation Epidemiology...
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Veröffentlicht in: | Annals of the Academy of Medicine, Singapore Singapore, 2013-09, Vol.42 (9), p.437-444 |
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creator | Goh, E Shaun Liang, Benjamin Fook-Chong, Stephanie Shahidah, Nur Soon, Swee Sung Yap, Susan Leong, Benjamin Gan, Han Nee Foo, David Tham, Lai Peng Charles, Rabind Ong, Marcus E H |
description | This study aims to study how the effect of the location of patient collapses from cardiac arrest, in the residential and non-residential areas within Singapore, relates to certain survival outcomes.
A retrospective cohort study of data were done from the Cardiac Arrest and Resuscitation Epidemiology (CARE) project. Out-of- hospital cardiac arrest (OHCA) data from October 2001 to October 2004 (CARE) were used. All patients with OHCA as confirmed by the absence of a pulse, unresponsiveness and apnoea were included. All events had occurred in Singapore. Analysis was performed and expressed in terms of the odds ratio (OR) and the corresponding 95% confidence interval (CI).
A total of 2375 cases were used for this analysis. Outcomes for OHCA in residential areas were poorer than in non-residential areas-1638 (68.9%) patients collapsed in residential areas, and 14 (0.9%) survived to discharge. This was significantly less than the 2.7% of patients who survived after collapsing in a non-residential area (OR 0.31 [0.16 - 0.62]). Multivariate logistic regression analysis showed that location alone had no independent effect on survival (adjusted OR 1.13 [0.32 - 4.05]); instead, underlying factors such as bystander CPR (OR 3.67 [1.13 - 11.97]) and initial shockable rhythms (OR 6.78 [1.95 - 23.53]) gave rise to better outcomes.
Efforts to improve survival from OHCA in residential areas should include increasing CPR by family members, and reducing ambulance response times. |
doi_str_mv | 10.47102/annals-acadmedsg.V42N9p437 |
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A retrospective cohort study of data were done from the Cardiac Arrest and Resuscitation Epidemiology (CARE) project. Out-of- hospital cardiac arrest (OHCA) data from October 2001 to October 2004 (CARE) were used. All patients with OHCA as confirmed by the absence of a pulse, unresponsiveness and apnoea were included. All events had occurred in Singapore. Analysis was performed and expressed in terms of the odds ratio (OR) and the corresponding 95% confidence interval (CI).
A total of 2375 cases were used for this analysis. Outcomes for OHCA in residential areas were poorer than in non-residential areas-1638 (68.9%) patients collapsed in residential areas, and 14 (0.9%) survived to discharge. This was significantly less than the 2.7% of patients who survived after collapsing in a non-residential area (OR 0.31 [0.16 - 0.62]). Multivariate logistic regression analysis showed that location alone had no independent effect on survival (adjusted OR 1.13 [0.32 - 4.05]); instead, underlying factors such as bystander CPR (OR 3.67 [1.13 - 11.97]) and initial shockable rhythms (OR 6.78 [1.95 - 23.53]) gave rise to better outcomes.
Efforts to improve survival from OHCA in residential areas should include increasing CPR by family members, and reducing ambulance response times.</description><identifier>ISSN: 0304-4602</identifier><identifier>EISSN: 0304-4602</identifier><identifier>DOI: 10.47102/annals-acadmedsg.V42N9p437</identifier><identifier>PMID: 24162318</identifier><language>eng</language><publisher>Singapore</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Ambulances ; Cardiopulmonary Resuscitation - statistics & numerical data ; Cohort Studies ; Emergency Medical Services - statistics & numerical data ; Female ; Geography ; Humans ; Logistic Models ; Male ; Middle Aged ; Multivariate Analysis ; Odds Ratio ; Out-of-Hospital Cardiac Arrest - mortality ; Residence Characteristics - statistics & numerical data ; Retrospective Studies ; Singapore - epidemiology ; Time-to-Treatment - statistics & numerical data ; Treatment Outcome</subject><ispartof>Annals of the Academy of Medicine, Singapore, 2013-09, Vol.42 (9), p.437-444</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c374t-b865a790e6939ce2ae86229974a7405240ab3bb236354853ba70ee9cb14547093</citedby><cites>FETCH-LOGICAL-c374t-b865a790e6939ce2ae86229974a7405240ab3bb236354853ba70ee9cb14547093</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24162318$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Goh, E Shaun</creatorcontrib><creatorcontrib>Liang, Benjamin</creatorcontrib><creatorcontrib>Fook-Chong, Stephanie</creatorcontrib><creatorcontrib>Shahidah, Nur</creatorcontrib><creatorcontrib>Soon, Swee Sung</creatorcontrib><creatorcontrib>Yap, Susan</creatorcontrib><creatorcontrib>Leong, Benjamin</creatorcontrib><creatorcontrib>Gan, Han Nee</creatorcontrib><creatorcontrib>Foo, David</creatorcontrib><creatorcontrib>Tham, Lai Peng</creatorcontrib><creatorcontrib>Charles, Rabind</creatorcontrib><creatorcontrib>Ong, Marcus E H</creatorcontrib><title>Effect of location of out-of-hospital cardiac arrest on survival outcomes</title><title>Annals of the Academy of Medicine, Singapore</title><addtitle>Ann Acad Med Singapore</addtitle><description>This study aims to study how the effect of the location of patient collapses from cardiac arrest, in the residential and non-residential areas within Singapore, relates to certain survival outcomes.
A retrospective cohort study of data were done from the Cardiac Arrest and Resuscitation Epidemiology (CARE) project. Out-of- hospital cardiac arrest (OHCA) data from October 2001 to October 2004 (CARE) were used. All patients with OHCA as confirmed by the absence of a pulse, unresponsiveness and apnoea were included. All events had occurred in Singapore. Analysis was performed and expressed in terms of the odds ratio (OR) and the corresponding 95% confidence interval (CI).
A total of 2375 cases were used for this analysis. Outcomes for OHCA in residential areas were poorer than in non-residential areas-1638 (68.9%) patients collapsed in residential areas, and 14 (0.9%) survived to discharge. This was significantly less than the 2.7% of patients who survived after collapsing in a non-residential area (OR 0.31 [0.16 - 0.62]). Multivariate logistic regression analysis showed that location alone had no independent effect on survival (adjusted OR 1.13 [0.32 - 4.05]); instead, underlying factors such as bystander CPR (OR 3.67 [1.13 - 11.97]) and initial shockable rhythms (OR 6.78 [1.95 - 23.53]) gave rise to better outcomes.
Efforts to improve survival from OHCA in residential areas should include increasing CPR by family members, and reducing ambulance response times.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Ambulances</subject><subject>Cardiopulmonary Resuscitation - statistics & numerical data</subject><subject>Cohort Studies</subject><subject>Emergency Medical Services - statistics & numerical data</subject><subject>Female</subject><subject>Geography</subject><subject>Humans</subject><subject>Logistic Models</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Multivariate Analysis</subject><subject>Odds Ratio</subject><subject>Out-of-Hospital Cardiac Arrest - mortality</subject><subject>Residence Characteristics - statistics & numerical data</subject><subject>Retrospective Studies</subject><subject>Singapore - epidemiology</subject><subject>Time-to-Treatment - statistics & numerical data</subject><subject>Treatment Outcome</subject><issn>0304-4602</issn><issn>0304-4602</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpNkF9LwzAUxYMobk6_ghR88aUz_5o0-CQydTD0RX0NN1mqlbapSTvw2xvdHD7dA_ecew8_hC4InnNJML2CroMm5mBh3bp1fJu_cvqoes7kAZpihnnOBaaH__QEncT4gTGXmIpjNKGcCMpIOUXLRVU5O2S-yhpvYah996P9OOS-yt997OsBmsxCWNdgMwjBxeTusjiGTb1Jq2S1vnXxFB1VqZY7280ZerlbPN8-5Kun--XtzSq3TPIhN6UoQCrshGLKOgquFJQqJTlIjgvKMRhmDGWCFbwsmAGJnVPWEF6k-orN0OX2bh_855ja6LaO1jUNdM6PURPORSkJwzRZr7dWG3yMwVW6D3UL4UsTrH9Z6i1LvWep9yxT-nz3aDRpt8_-wWPfwbZ1Dg</recordid><startdate>20130901</startdate><enddate>20130901</enddate><creator>Goh, E Shaun</creator><creator>Liang, Benjamin</creator><creator>Fook-Chong, Stephanie</creator><creator>Shahidah, Nur</creator><creator>Soon, Swee Sung</creator><creator>Yap, Susan</creator><creator>Leong, Benjamin</creator><creator>Gan, Han Nee</creator><creator>Foo, David</creator><creator>Tham, Lai Peng</creator><creator>Charles, Rabind</creator><creator>Ong, Marcus E H</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20130901</creationdate><title>Effect of location of out-of-hospital cardiac arrest on survival outcomes</title><author>Goh, E Shaun ; Liang, Benjamin ; Fook-Chong, Stephanie ; Shahidah, Nur ; Soon, Swee Sung ; Yap, Susan ; Leong, Benjamin ; Gan, Han Nee ; Foo, David ; Tham, Lai Peng ; Charles, Rabind ; Ong, Marcus E H</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c374t-b865a790e6939ce2ae86229974a7405240ab3bb236354853ba70ee9cb14547093</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Ambulances</topic><topic>Cardiopulmonary Resuscitation - statistics & numerical data</topic><topic>Cohort Studies</topic><topic>Emergency Medical Services - statistics & numerical data</topic><topic>Female</topic><topic>Geography</topic><topic>Humans</topic><topic>Logistic Models</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Multivariate Analysis</topic><topic>Odds Ratio</topic><topic>Out-of-Hospital Cardiac Arrest - mortality</topic><topic>Residence Characteristics - statistics & numerical data</topic><topic>Retrospective Studies</topic><topic>Singapore - epidemiology</topic><topic>Time-to-Treatment - statistics & numerical data</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Goh, E Shaun</creatorcontrib><creatorcontrib>Liang, Benjamin</creatorcontrib><creatorcontrib>Fook-Chong, Stephanie</creatorcontrib><creatorcontrib>Shahidah, Nur</creatorcontrib><creatorcontrib>Soon, Swee Sung</creatorcontrib><creatorcontrib>Yap, Susan</creatorcontrib><creatorcontrib>Leong, Benjamin</creatorcontrib><creatorcontrib>Gan, Han Nee</creatorcontrib><creatorcontrib>Foo, David</creatorcontrib><creatorcontrib>Tham, Lai Peng</creatorcontrib><creatorcontrib>Charles, Rabind</creatorcontrib><creatorcontrib>Ong, Marcus E H</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Annals of the Academy of Medicine, Singapore</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Goh, E Shaun</au><au>Liang, Benjamin</au><au>Fook-Chong, Stephanie</au><au>Shahidah, Nur</au><au>Soon, Swee Sung</au><au>Yap, Susan</au><au>Leong, Benjamin</au><au>Gan, Han Nee</au><au>Foo, David</au><au>Tham, Lai Peng</au><au>Charles, Rabind</au><au>Ong, Marcus E H</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of location of out-of-hospital cardiac arrest on survival outcomes</atitle><jtitle>Annals of the Academy of Medicine, Singapore</jtitle><addtitle>Ann Acad Med Singapore</addtitle><date>2013-09-01</date><risdate>2013</risdate><volume>42</volume><issue>9</issue><spage>437</spage><epage>444</epage><pages>437-444</pages><issn>0304-4602</issn><eissn>0304-4602</eissn><abstract>This study aims to study how the effect of the location of patient collapses from cardiac arrest, in the residential and non-residential areas within Singapore, relates to certain survival outcomes.
A retrospective cohort study of data were done from the Cardiac Arrest and Resuscitation Epidemiology (CARE) project. Out-of- hospital cardiac arrest (OHCA) data from October 2001 to October 2004 (CARE) were used. All patients with OHCA as confirmed by the absence of a pulse, unresponsiveness and apnoea were included. All events had occurred in Singapore. Analysis was performed and expressed in terms of the odds ratio (OR) and the corresponding 95% confidence interval (CI).
A total of 2375 cases were used for this analysis. Outcomes for OHCA in residential areas were poorer than in non-residential areas-1638 (68.9%) patients collapsed in residential areas, and 14 (0.9%) survived to discharge. This was significantly less than the 2.7% of patients who survived after collapsing in a non-residential area (OR 0.31 [0.16 - 0.62]). Multivariate logistic regression analysis showed that location alone had no independent effect on survival (adjusted OR 1.13 [0.32 - 4.05]); instead, underlying factors such as bystander CPR (OR 3.67 [1.13 - 11.97]) and initial shockable rhythms (OR 6.78 [1.95 - 23.53]) gave rise to better outcomes.
Efforts to improve survival from OHCA in residential areas should include increasing CPR by family members, and reducing ambulance response times.</abstract><cop>Singapore</cop><pmid>24162318</pmid><doi>10.47102/annals-acadmedsg.V42N9p437</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adult Aged Aged, 80 and over Ambulances Cardiopulmonary Resuscitation - statistics & numerical data Cohort Studies Emergency Medical Services - statistics & numerical data Female Geography Humans Logistic Models Male Middle Aged Multivariate Analysis Odds Ratio Out-of-Hospital Cardiac Arrest - mortality Residence Characteristics - statistics & numerical data Retrospective Studies Singapore - epidemiology Time-to-Treatment - statistics & numerical data Treatment Outcome |
title | Effect of location of out-of-hospital cardiac arrest on survival outcomes |
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