Outcomes of Alpha 1,3-GT-knockout Porcine Heart Transplants Into a Preclinical Nonhuman Primate Model

Abstract Background Solid organ xenotransplantation is a potential solution to current organ shortages in allotransplantation. We performed four heart transplantations from alpha1, 3-galactosyltransferase gene-knockout (GT-KO) pigs to cynomolgus monkeys and monitored immunological parameters before...

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Veröffentlicht in:	Transplantation proceedings 2013-10, Vol.45 (8), p.3085-3091
Hauptverfasser:	Kim, H, Chee, H.K, Yang, J, Hwang, S, Han, K.H, Kang, J, Park, J.H, Kim, J.S, Lee, S.J, Ock, S.A, Park, M.H, Park, K.S, Byeongchun, L, Cho, K, Noh, J, Park, W, Yun, I.J, Ahn, C
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Disease Models, Animal Galactosyltransferases - genetics Gene Knockdown Techniques Graft Survival Heart Transplantation Immunosuppressive Agents - administration & dosage Macaca fascicularis Surgery Swine
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