Extracellular Signal-Regulated Kinase Regulates RhoA Activation and Tumor Cell Plasticity by Inhibiting Guanine Exchange Factor H1 Activity
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Veröffentlicht in: | Molecular and Cellular Biology 2013-11, Vol.33 (22), p.4526-4537 |
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creator | von Thun, Anne Preisinger, Christian Rath, Oliver Schwarz, Juliane P. Ward, Chris Monsefi, Naser Rodríguez, Javier Garcia-Munoz, Amaya Birtwistle, Marc Bienvenut, Willy Anderson, Kurt I. Kolch, Walter von Kriegsheim, Alex |
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</description><identifier>ISSN: 0270-7306</identifier><identifier>ISSN: 1098-5549</identifier><identifier>EISSN: 1098-5549</identifier><identifier>DOI: 10.1128/MCB.00585-13</identifier><identifier>PMID: 24043311</identifier><language>eng</language><publisher>United States: American Society for Microbiology</publisher><subject>Amino Acid Sequence ; Animals ; Cell Line, Tumor ; Cell Movement ; Enzyme Activation ; Extracellular Signal-Regulated MAP Kinases - metabolism ; HEK293 Cells ; Humans ; Molecular Sequence Data ; Mutation ; Neoplasm Invasiveness - genetics ; Neoplasm Invasiveness - pathology ; Neoplasms - genetics ; Neoplasms - metabolism ; Neoplasms - pathology ; Phosphorylation ; Proto-Oncogene Proteins c-fos - metabolism ; Rats ; Rho Guanine Nucleotide Exchange Factors - chemistry ; Rho Guanine Nucleotide Exchange Factors - genetics ; Rho Guanine Nucleotide Exchange Factors - metabolism ; rhoA GTP-Binding Protein - metabolism ; RNA Interference ; Signal Transduction</subject><ispartof>Molecular and Cellular Biology, 2013-11, Vol.33 (22), p.4526-4537</ispartof><rights>Copyright © 2013, American Society for Microbiology 2013</rights><rights>Copyright © 2013, American Society for Microbiology. All Rights Reserved. 2013 American Society for Microbiology</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c459t-caac76906fcd4580a552ba973ec73b08aa71eacfdd8ca6b1ec26d5cd8bc6afd03</citedby><cites>FETCH-LOGICAL-c459t-caac76906fcd4580a552ba973ec73b08aa71eacfdd8ca6b1ec26d5cd8bc6afd03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838172/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838172/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24043311$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>von Thun, Anne</creatorcontrib><creatorcontrib>Preisinger, Christian</creatorcontrib><creatorcontrib>Rath, Oliver</creatorcontrib><creatorcontrib>Schwarz, Juliane P.</creatorcontrib><creatorcontrib>Ward, Chris</creatorcontrib><creatorcontrib>Monsefi, Naser</creatorcontrib><creatorcontrib>Rodríguez, Javier</creatorcontrib><creatorcontrib>Garcia-Munoz, Amaya</creatorcontrib><creatorcontrib>Birtwistle, Marc</creatorcontrib><creatorcontrib>Bienvenut, Willy</creatorcontrib><creatorcontrib>Anderson, Kurt I.</creatorcontrib><creatorcontrib>Kolch, Walter</creatorcontrib><creatorcontrib>von Kriegsheim, Alex</creatorcontrib><title>Extracellular Signal-Regulated Kinase Regulates RhoA Activation and Tumor Cell Plasticity by Inhibiting Guanine Exchange Factor H1 Activity</title><title>Molecular and Cellular Biology</title><addtitle>Mol Cell Biol</addtitle><description>Article Usage Stats
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</description><subject>Amino Acid Sequence</subject><subject>Animals</subject><subject>Cell Line, Tumor</subject><subject>Cell Movement</subject><subject>Enzyme Activation</subject><subject>Extracellular Signal-Regulated MAP Kinases - metabolism</subject><subject>HEK293 Cells</subject><subject>Humans</subject><subject>Molecular Sequence Data</subject><subject>Mutation</subject><subject>Neoplasm Invasiveness - genetics</subject><subject>Neoplasm Invasiveness - pathology</subject><subject>Neoplasms - genetics</subject><subject>Neoplasms - metabolism</subject><subject>Neoplasms - pathology</subject><subject>Phosphorylation</subject><subject>Proto-Oncogene Proteins c-fos - metabolism</subject><subject>Rats</subject><subject>Rho Guanine Nucleotide Exchange Factors - chemistry</subject><subject>Rho Guanine Nucleotide Exchange Factors - genetics</subject><subject>Rho Guanine Nucleotide Exchange Factors - metabolism</subject><subject>rhoA GTP-Binding Protein - metabolism</subject><subject>RNA Interference</subject><subject>Signal Transduction</subject><issn>0270-7306</issn><issn>1098-5549</issn><issn>1098-5549</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kc1u1DAURiMEokNhxxpZrFiQYsdx4myQhtH0RxSBSllbN7aTGCV2aztt5xn60nVJW8GClWX73OPr-2XZW4IPCCn4p2-bLwcYM85yQp9lK4IbnjNWNs-zFS5qnNcUV3vZqxB-Y4yrBtOX2V5R4pJSQlbZ7fYmepB6HOcRPPppegtjfqb7tI1aoa_GQtDo8SCgs8Gt0VpGcwXROIvAKnQ-T86jTZKgHyOEaKSJO9Tu0IkdTGuisT06msEaq9H2Rg5ge40OQcZUdUwWW6p4nb3oYAz6zcO6n_063J5vjvPT70cnm_VpLkvWxFwCyDp9pOqkKhnHwFjRQlNTLWvaYg5QEw2yU4pLqFqiZVEpJhVvZQWdwnQ_-7x4L-Z20kpqm0YwigtvJvA74cCIf2-sGUTvrgTllJO6SIIPDwLvLmcdophMuJ8hWO3mIEiZGiWkJjyhHxdUeheC193TMwSL-_xEyk_8yU8QmvB3f7f2BD8GloB6AYztnJ_g2vlRiQi70fnOg5UmCPof9fulcjD9cG28FhAmMclWUCqKQpSsqOgdfGi3zA</recordid><startdate>20131101</startdate><enddate>20131101</enddate><creator>von Thun, Anne</creator><creator>Preisinger, Christian</creator><creator>Rath, Oliver</creator><creator>Schwarz, Juliane P.</creator><creator>Ward, Chris</creator><creator>Monsefi, Naser</creator><creator>Rodríguez, Javier</creator><creator>Garcia-Munoz, Amaya</creator><creator>Birtwistle, Marc</creator><creator>Bienvenut, Willy</creator><creator>Anderson, Kurt I.</creator><creator>Kolch, Walter</creator><creator>von Kriegsheim, Alex</creator><general>American Society for Microbiology</general><general>Taylor & Francis</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20131101</creationdate><title>Extracellular Signal-Regulated Kinase Regulates RhoA Activation and Tumor Cell Plasticity by Inhibiting Guanine Exchange Factor H1 Activity</title><author>von Thun, Anne ; 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subjects | Amino Acid Sequence Animals Cell Line, Tumor Cell Movement Enzyme Activation Extracellular Signal-Regulated MAP Kinases - metabolism HEK293 Cells Humans Molecular Sequence Data Mutation Neoplasm Invasiveness - genetics Neoplasm Invasiveness - pathology Neoplasms - genetics Neoplasms - metabolism Neoplasms - pathology Phosphorylation Proto-Oncogene Proteins c-fos - metabolism Rats Rho Guanine Nucleotide Exchange Factors - chemistry Rho Guanine Nucleotide Exchange Factors - genetics Rho Guanine Nucleotide Exchange Factors - metabolism rhoA GTP-Binding Protein - metabolism RNA Interference Signal Transduction |
title | Extracellular Signal-Regulated Kinase Regulates RhoA Activation and Tumor Cell Plasticity by Inhibiting Guanine Exchange Factor H1 Activity |
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