Are anti-inflammatory properties of lipoic acid associated with the formation of hydrogen sulfide?

Lipoic acid (LA) was shown to possess anti-inflammatory properties. In this study, we present evidence supporting the hypothesis that the anti-inflammatory properties of LA are associated with the formation of hydrogen sulfide (H2S). The study was conducted on male albino Swiss mice. The animals wer...

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Veröffentlicht in:	Pharmacological reports 2013, Vol.65 (4), p.1018-1024
Hauptverfasser:	Dudek, Magdalena, Bilska-Wilkosz, Anna, Knutelska, Joanna, Mogilski, Szczepan, Bednarski, Marek, Zygmunt, Małgorzata, Iciek, Małgorzata, Sapa, Jacek, Bugajski, Dominik, Filipek, Barbara, Włodek, Lidia
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents - pharmacology Anti-Inflammatory Agents - therapeutic use anti-inflammatory properties Carrageenan carrageenan-induced paw edema dihydrolipoic acid Dose-Response Relationship, Drug Drug Safety and Pharmacovigilance Edema - chemically induced Edema - drug therapy glibenclamide Glyburide - pharmacology Hindlimb - drug effects hydrogen sulfide Hydrogen Sulfide - metabolism Indomethacin - pharmacology Indomethacin - therapeutic use lipoic acid Male Mice Pharmacotherapy Pharmacy Potassium Channel Blockers - pharmacology Short Communication Thioctic Acid - antagonists & inhibitors Thioctic Acid - pharmacology Thioctic Acid - therapeutic use
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