Biological monitoring for mutagenic effects of occupational exposure to butadiene

The use of biological markers in the evaluation of human exposure to hazardous agents has increased rapidly in recent years. Because 1,3-butadiene is a mutagenic carcinogen, existing occupational levels of exposure may be appropriately evaluated using somatic cell mutation as a biomarker. Previously...

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Veröffentlicht in:	Toxicology (Amsterdam) 1996-10, Vol.113 (1), p.84-90
Hauptverfasser:	Ward, Jonathan B., Ammenheuser, Marinel M., Whorton, Elbert B., Bechtold, William E., Kelsey, Karl T., Legator, Marvin S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Biological monitoring Butadiene Butadienes - toxicity Chemical mutagenesis Environmental Monitoring hprt mutation Human Humans Hypoxanthine Phosphoribosyltransferase - genetics Medical sciences Mutagens - toxicity Mutation Occupational Exposure - adverse effects Occupational health Rubber Smoking - adverse effects Styrene Styrenes - toxicity Toxicology
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