Differential apoptosis in BeWo cells after infection with highly (RH) or moderately (ME49) virulent strains of Toxoplasma gondii is related to the cytokine profile secreted, the death receptor Fas expression and phosphorylated ERK1/2 expression

Abstract Introduction Alterations of apoptosis are commonly associated with pregnancy complications and abortion. Modulation of apoptosis is a relevant feature of Toxoplasma gondii infection and it is related to parasite strain types. The aim of the present study was to evaluate the possible factors...

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Veröffentlicht in:	Placenta (Eastbourne) 2013-11, Vol.34 (11), p.973-982
Hauptverfasser:	Angeloni, M.B, Guirelli, P.M, Franco, P.S, Barbosa, B.F, Gomes, A.O, Castro, A.S, Silva, N.M, Martins-Filho, O.A, Mineo, T.W.P, Silva, D.A.O, Mineo, J.R, Ferro, E.A.V
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis BeWo cells Biological and medical sciences Cell Line Congenital toxoplasmosis Cytokines - genetics Cytokines - metabolism Cytokines - secretion Embryology: invertebrates and vertebrates. Teratology fas Receptor - biosynthesis fas Receptor - metabolism Female Fundamental and applied biological sciences. Psychology Humans Internal Medicine Mitogen-Activated Protein Kinase 1 - biosynthesis Mitogen-Activated Protein Kinase 1 - metabolism Mitogen-Activated Protein Kinase 3 - biosynthesis Mitogen-Activated Protein Kinase 3 - metabolism Obstetrics and Gynecology Phosphorylation Placenta - immunology Placenta - metabolism Placenta - parasitology Placenta - secretion Placentation Pregnancy Pregnancy Complications, Parasitic - immunology Pregnancy Complications, Parasitic - metabolism Pregnancy Complications, Parasitic - parasitology Pregnancy Complications, Parasitic - pathology Protein Processing, Post-Translational Recombinant Proteins - metabolism Species Specificity Toxoplasma - immunology Toxoplasma - pathogenicity Toxoplasma gondii Toxoplasmosis - immunology Toxoplasmosis - metabolism Toxoplasmosis - parasitology Toxoplasmosis - pathology Trophoblastic cells Trophoblasts - immunology Trophoblasts - metabolism Trophoblasts - parasitology Trophoblasts - secretion Up-Regulation Virulence
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