Macrophage polarization following chitosan implantation

Abstract Macrophages are a key cell in the host response to implants and can be polarized into different phenotypes capable of inducing both detrimental and beneficial outcomes in tissue repair and remodeling, being important in tissue engineering and regenerative medicine. The objective of this stu...

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Veröffentlicht in:	Biomaterials 2013-12, Vol.34 (38), p.9952-9959
Hauptverfasser:	Vasconcelos, Daniela P, Fonseca, Ana C, Costa, Madalena, Amaral, Isabel F, Barbosa, Mário A, Águas, Artur P, Barbosa, Judite N
Format:	Artikel
Sprache:	eng
Schlagworte:	Advanced Basic Science Animals Chitosan Chitosan - chemistry Dentistry Flow Cytometry Inflammation Inflammation - metabolism Interleukin-4 - metabolism Interleukin-6 - metabolism In vivo studies Macrophage polarization Macrophages - cytology Macrophages - metabolism Male Mice Mice, Inbred BALB C Microscopy, Confocal Tissue Engineering - methods Tissue Scaffolds - chemistry Tumor Necrosis Factor-alpha - metabolism
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