Animal models and therapeutic prospects for Charcot-Marie-Tooth disease

Charcot–Marie–Tooth (CMT) neuropathies are inherited neuromuscular disorders caused by a length‐dependent neurodegeneration of peripheral nerves. More than 900 mutations in 60 different genes are causative of the neuropathy. Despite significant progress in therapeutic strategies, the disease remains...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Annals of neurology 2013-09, Vol.74 (3), p.391-396
Hauptverfasser:	Bouhy, Delphine, Timmerman, Vincent
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Genetically Modified Charcot-Marie-Tooth Disease - genetics Charcot-Marie-Tooth Disease - therapy Disease Models, Animal Humans Medical research Mutation Transgenic animals
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!