Organocatalyzed Three-Component Ugi and Passerini Reactions of 4‑Oxoazetidine-2-carbaldehydes and Azetidine-2,3-diones. Application to the Synthesis of γ‑Lactams and γ‑Lactones

The organocatalyzed U-3CR of 4-oxoazetidine-2-carbaldehydes has been studied. In addition, the organocatalyzed P-3CR of 4-oxoazetidine-2-carbaldehydes and azetidine-2,3-diones has been described for the first time. U-3CR and P-3CR adducts have been obtained in good yields and reasonable diastereosel...

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Veröffentlicht in:	Journal of organic chemistry 2013-10, Vol.78 (20), p.10154-10165
Hauptverfasser:	Alcaide, Benito, Almendros, Pedro, Aragoncillo, Cristina, Callejo, Ricardo, Ruiz, M. Pilar
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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