Development, Purification, and Characterization of Monoclonal Antibodies Against Recombinant Histidine-rich Protein 3 of Plasmodium falciparum

In the present study, monoclonal antibodies (MAbs) against recombinant histidine-rich protein (rHRP3) were developed and assessed for their potential in detection of Plasmodium falciparum HRP3. Hybridomas were obtained by fusion of Sp2/0 mouse myeloma cells and spleen cells from the mouse immunized...

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Veröffentlicht in:	Monoclonal antibodies in immunodiagnosis and immunotherapy 2013-10, Vol.32 (5), p.341-348
Hauptverfasser:	Palani, B., Ranjini, S. Shiva, Jayaprakash, N.S., Vijayalakshmi, M.A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - biosynthesis Antibodies, Monoclonal - genetics Antigens, Protozoan - immunology Enzyme-Linked Immunosorbent Assay - methods Hybridomas - cytology Hybridomas - metabolism Immunoblotting Malaria - diagnosis Mice Original Articles Plasmodium falciparum - immunology Plasmodium falciparum - metabolism Protozoan Proteins - immunology Rabbits Recombinant Proteins - immunology Sensitivity and Specificity Spleen - cytology Tumor Cells, Cultured
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