Alterations of cortical excitability and central motor conduction time in Wilson's disease

•In Wilson's disease (WD) there are structural alterations of brain.•Transcranial magnetic stimulation (TMS) can evaluate neurophysiological changes.•Thirteen patients with WD were studied using TMS.•Non-recordable or high RMT and prolonged CMCT were observed in WD.•Patients with WD have widesp...

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Veröffentlicht in:	Neuroscience letters 2013-10, Vol.553, p.90-94
Hauptverfasser:	Jhunjhunwala, Ketan, Prashanth, D.K., Netravathi, M., Nagaraju, B.C., Pal, Pramod Kr
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Central motor conduction time Cerebral Cortex - physiopathology Child Cortical excitability Evoked Potentials, Motor Female Hepatolenticular Degeneration - drug therapy Hepatolenticular Degeneration - physiopathology Humans Magnetic Resonance Imaging Male Penicillamine - therapeutic use Resting motor threshold Time Factors Transcranial Magnetic Stimulation Wilson's disease Young Adult Zinc Sulfate - therapeutic use
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