Chemical Composition and Biological Activity of Conyza Bonariensis Essential Oil Collected in Mérida, Venezuela
The essential oil from aerial parts of Conyza bonariensis (L) Cronquist collected in Mérida was obtained by hydrodistillation and analysed by GC/MS. The major components were trans-β-farnesene (37.8%), trans-ocimene (20.7%) and β-sesquiphellandrene (9.8%). Cytotoxicity assay was also performed with...
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| Veröffentlicht in: | Natural product communications 2013-08, Vol.8 (8), p.1175-1178 |
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| creator | Araujo, Liliana Moujir, Laila M. Rojas, Janne Rojas, Luis Carmona, Juan Rondón, María |
| description | The essential oil from aerial parts of Conyza bonariensis (L) Cronquist collected in Mérida was obtained by hydrodistillation and analysed by GC/MS. The major components were trans-β-farnesene (37.8%), trans-ocimene (20.7%) and β-sesquiphellandrene (9.8%). Cytotoxicity assay was also performed with the essential oil against HeLa (cervix carcinoma), A-459 (lung carcinoma) and MCF-7 (breast adenocarcinoma) human cell lines and against normal Vero cells (African green monkey kidney) with IC50 values ranging from 1.4 to 45.8 μg/mL. Additionally, the essential oil presented a significant bactericidal effect against Bacillus cereus, while a moderate activity was observed against Staphylococcus epidermidis and Candida albicans. |
| doi_str_mv | 10.1177/1934578X1300800838 |
| format | Article |
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The major components were trans-β-farnesene (37.8%), trans-ocimene (20.7%) and β-sesquiphellandrene (9.8%). Cytotoxicity assay was also performed with the essential oil against HeLa (cervix carcinoma), A-459 (lung carcinoma) and MCF-7 (breast adenocarcinoma) human cell lines and against normal Vero cells (African green monkey kidney) with IC50 values ranging from 1.4 to 45.8 μg/mL. Additionally, the essential oil presented a significant bactericidal effect against Bacillus cereus, while a moderate activity was observed against Staphylococcus epidermidis and Candida albicans.</description><subject>Animals</subject><subject>Anti-Infective Agents - analysis</subject><subject>Antineoplastic Agents, Phytogenic - analysis</subject><subject>Cercopithecus aethiops</subject><subject>Conyza - chemistry</subject><subject>Drug Screening Assays, Antitumor</subject><subject>Gas Chromatography-Mass Spectrometry</subject><subject>HeLa Cells</subject><subject>Humans</subject><subject>MCF-7 Cells</subject><subject>Microbial Sensitivity Tests</subject><subject>Oils, Volatile - chemistry</subject><subject>Venezuela</subject><subject>Vero Cells</subject><issn>1934-578X</issn><issn>1555-9475</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpl0d1KwzAUB_AgihtzL-CF5NIL65omWZLLrcwPmOxGxbuSpunMaJPatML2Rj6HL2bm5pUhkAPnx-GQPwCXKL5FiLEJEphQxt8QjmMeLuYnYIgopZEgjJ6GOoBoLwZg7P0mDodzEhNxDgYJiZlAgg9Bk77r2ihZwdTVjfOmM85CaQs4N65y69_WTHXm03Rb6MrA7HYn4dxZ2RptvfFw4b22nQlwZfZzqkqrThfQWPj0_dWaQt7AV231rteVvABnpay8Hh_fEXi5WzynD9Fydf-YzpZRkwjaRUwRlPNSFlOWMKySKdYoJ0pyUeQqTxJOqKRCCpoooVguEBexohILrLks8xyPwPVhbtO6j177LquNV7qqpNWu9xkiBGORTBEK9OpI-7zWRda0ppbtNvv7pQAmB-DlWmcb17c2rJ6hONtHkf2PAv8AYxZ6Ig</recordid><startdate>20130801</startdate><enddate>20130801</enddate><creator>Araujo, Liliana</creator><creator>Moujir, Laila M.</creator><creator>Rojas, Janne</creator><creator>Rojas, Luis</creator><creator>Carmona, Juan</creator><creator>Rondón, María</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20130801</creationdate><title>Chemical Composition and Biological Activity of Conyza Bonariensis Essential Oil Collected in Mérida, Venezuela</title><author>Araujo, Liliana ; Moujir, Laila M. ; Rojas, Janne ; Rojas, Luis ; Carmona, Juan ; Rondón, María</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p295t-7c41b8fad67273c263e1b4ca89dbcb22845a59a952c9c7b91890c5a393e8afbb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Animals</topic><topic>Anti-Infective Agents - analysis</topic><topic>Antineoplastic Agents, Phytogenic - analysis</topic><topic>Cercopithecus aethiops</topic><topic>Conyza - chemistry</topic><topic>Drug Screening Assays, Antitumor</topic><topic>Gas Chromatography-Mass Spectrometry</topic><topic>HeLa Cells</topic><topic>Humans</topic><topic>MCF-7 Cells</topic><topic>Microbial Sensitivity Tests</topic><topic>Oils, Volatile - chemistry</topic><topic>Venezuela</topic><topic>Vero Cells</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Araujo, Liliana</creatorcontrib><creatorcontrib>Moujir, Laila M.</creatorcontrib><creatorcontrib>Rojas, Janne</creatorcontrib><creatorcontrib>Rojas, Luis</creatorcontrib><creatorcontrib>Carmona, Juan</creatorcontrib><creatorcontrib>Rondón, María</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Natural product communications</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Araujo, Liliana</au><au>Moujir, Laila M.</au><au>Rojas, Janne</au><au>Rojas, Luis</au><au>Carmona, Juan</au><au>Rondón, María</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Chemical Composition and Biological Activity of Conyza Bonariensis Essential Oil Collected in Mérida, Venezuela</atitle><jtitle>Natural product communications</jtitle><addtitle>Nat Prod Commun</addtitle><date>2013-08-01</date><risdate>2013</risdate><volume>8</volume><issue>8</issue><spage>1175</spage><epage>1178</epage><pages>1175-1178</pages><issn>1934-578X</issn><eissn>1555-9475</eissn><abstract>The essential oil from aerial parts of Conyza bonariensis (L) Cronquist collected in Mérida was obtained by hydrodistillation and analysed by GC/MS. 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| language | eng |
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| source | Sage Journals GOLD Open Access 2024 |
| subjects | Animals Anti-Infective Agents - analysis Antineoplastic Agents, Phytogenic - analysis Cercopithecus aethiops Conyza - chemistry Drug Screening Assays, Antitumor Gas Chromatography-Mass Spectrometry HeLa Cells Humans MCF-7 Cells Microbial Sensitivity Tests Oils, Volatile - chemistry Venezuela Vero Cells |
| title | Chemical Composition and Biological Activity of Conyza Bonariensis Essential Oil Collected in Mérida, Venezuela |
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