Polyacetylenes from the leaves of Vernonia scorpioides (Asteraceae) and their antiproliferative and antiherpetic activities

Seven polyacetylenes were isolated from Vernonia scorpioides and tested against Herpes virus and against non-small cell lung cancer A549. All the structures of the isolated compounds were determined based on extensive analysis of 1D and 2D NMR and MS data. •All structures were established based on e...

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Veröffentlicht in:	Phytochemistry (Oxford) 2013-11, Vol.95, p.375-383
Hauptverfasser:	Pollo, Luiz A.E., Bosi, Cristiane F., Leite, Andrea S., Rigotto, Caroline, Kratz, Jadel, Simões, Claudia M.O., Fonseca, David E.P., Coimbra, Daniel, Caramori, Giovanni, Nepel, Angelita, Campos, Francinete R., Barison, Andersson, Biavatti, Maique W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiproliferative Antiviral Agents - chemistry Antiviral Agents - isolation & purification Antiviral Agents - pharmacology antiviral properties Apiaceae Araliaceae Asteraceae Cell Line, Tumor glycosides Herpes simplex virus HSV Humans leaves lung neoplasms Medicine, Traditional Molecular Structure nuclear magnetic resonance spectroscopy Plant Extracts - chemistry Plant Extracts - pharmacology Plant Leaves - chemistry Polyacetylenes Polyacetylenes - chemistry Polyacetylenes - isolation & purification Polyacetylenes - pharmacology Simplexvirus - drug effects Small Cell Lung Carcinoma - drug therapy tropics Vernonia Vernonia - chemistry Vernonia scorpioides
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