Microfluidic Fabrication of Stable Gas-Filled Microcapsules for Acoustic Contrast Enhancement

We introduce a facile approach for the production of gas-filled microcapsules designed to withstand high pressures. We exploit microfluidics to fabricate water-filled microcapsules that are then externally triggered to become gas-filled, thus making them more echogenic. In addition, the gas-filled m...

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Veröffentlicht in:Langmuir 2013-10, Vol.29 (40), p.12352-12357
Hauptverfasser: Abbaspourrad, Alireza, Duncanson, Wynter J, Lebedeva, Natalia, Kim, Shin-Hyun, Zhushma, Aleksandr P, Datta, Sujit S, Dayton, Paul A, Sheiko, Sergei S, Rubinstein, Michael, Weitz, David A
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container_end_page 12357
container_issue 40
container_start_page 12352
container_title Langmuir
container_volume 29
creator Abbaspourrad, Alireza
Duncanson, Wynter J
Lebedeva, Natalia
Kim, Shin-Hyun
Zhushma, Aleksandr P
Datta, Sujit S
Dayton, Paul A
Sheiko, Sergei S
Rubinstein, Michael
Weitz, David A
description We introduce a facile approach for the production of gas-filled microcapsules designed to withstand high pressures. We exploit microfluidics to fabricate water-filled microcapsules that are then externally triggered to become gas-filled, thus making them more echogenic. In addition, the gas-filled microcapsules have a solid polymer shell making them resistant to pressure-induced buckling, which makes them more mechanically robust than traditional prestabilized microbubbles; this should increase the potential of their utility for acoustic imaging of porous media with high hydrostatic pressures such as oil reservoirs.
doi_str_mv 10.1021/la402598p
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source MEDLINE; American Chemical Society Journals
subjects Acoustics
Capsules
Chemistry
Colloidal state and disperse state
Exact sciences and technology
General and physical chemistry
Microfluidics - methods
Porous materials
title Microfluidic Fabrication of Stable Gas-Filled Microcapsules for Acoustic Contrast Enhancement
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