Effect of Early Metoprolol on Infarct Size in ST-Segment–Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention: The Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) Trial

BACKGROUND—The effect of β-blockers on infarct size when used in conjunction with primary percutaneous coronary intervention is unknown. We hypothesize that metoprolol reduces infarct size when administered early (intravenously before reperfusion). METHODS AND RESULTS—Patients with Killip class II o...

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Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 2013-10, Vol.128 (14), p.1495-1503
Hauptverfasser:	Ibanez, Borja, Macaya, Carlos, Sánchez-Brunete, Vicente, Pizarro, Gonzalo, Fernández-Friera, Leticia, Mateos, Alonso, Fernández-Ortiz, Antonio, García-Ruiz, José M., García-Álvarez, Ana, Iñiguez, Andrés, Jiménez-Borreguero, Jesús, López-Romero, Pedro, Fernández-Jiménez, Rodrigo, Goicolea, Javier, Ruiz-Mateos, Borja, Bastante, Teresa, Arias, Mercedes, Iglesias-Vázquez, José A., Rodriguez, Maite D., Escalera, Noemí, Acebal, Carlos, Cabrera, José A., Valenciano, Juan, Pérez de Prado, Armando, Fernández-Campos, María J., Casado, Isabel, García-Rubira, Juan C., García-Prieto, Jaime, Sanz-Rosa, David, Cuellas, Carlos, Hernández-Antolín, Rosana, Albarrán, Agustín, Fernández-Vázquez, Felipe, de la Torre-Hernández, José M., Pocock, Stuart, Sanz, Ginés, Fuster, Valentin
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic beta-Antagonists - administration & dosage Adrenergic beta-Antagonists - therapeutic use Antiarythmic agents Biological and medical sciences Biomarkers Blood and lymphatic vessels Cardiology. Vascular system Cardiotonic Agents - administration & dosage Cardiotonic Agents - therapeutic use Cardiovascular system Combined Modality Therapy Coronary heart disease Creatine Kinase, MB Form - blood Diseases of the cardiovascular system Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous Female Fibrinolytic Agents - administration & dosage Fibrinolytic Agents - therapeutic use Heart Heart Failure - prevention & control Humans Magnetic Resonance Imaging Male Medical sciences Metoprolol - administration & dosage Metoprolol - therapeutic use Middle Aged Myocardial Infarction - drug therapy Myocardial Infarction - pathology Myocardial Infarction - physiopathology Myocardial Infarction - surgery Myocardium - pathology Necrosis Percutaneous Coronary Intervention Pharmacology. Drug treatments Premedication Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Single-Blind Method Stroke Volume - drug effects Thrombolytic Therapy
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