Differentially Altered Molecular Signature of Visceral Adipose Tissue in HIV-1–Associated Lipodystrophy

OBJECTIVE:Lipodystrophy in HIV-1–infected antiretroviral-treated patients is often associated with opposite alterations in adipose tissue depots as followslipoatrophy of subcutaneous adipose tissue (SAT) versus lipohypertrophy of visceral adipose tissue (VAT). We determined the specific molecular al...

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Veröffentlicht in:	Journal of acquired immune deficiency syndromes (1999) 2013-10, Vol.64 (2), p.142-148
Hauptverfasser:	Gallego-Escuredo, José M., Villarroya, Joan, Domingo, Pere, Targarona, Eduard M., Alegre, Marta, Domingo, Joan C., Villarroya, Francesc, Giralt, Marta
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipogenesis - genetics Adult AIDS/HIV Antiretroviral drugs Antiretroviral Therapy, Highly Active Cytokines - genetics Cytokines - metabolism DNA, Mitochondrial - analysis DNA, Mitochondrial - genetics Female Gene Expression HIV HIV Infections - complications HIV Infections - drug therapy HIV Infections - genetics HIV-1 - drug effects HIV-1 - pathogenicity HIV-Associated Lipodystrophy Syndrome - genetics HIV-Associated Lipodystrophy Syndrome - pathology Human immunodeficiency virus Humans Indexing in process Inflammation - genetics Inflammation - metabolism Intra-Abdominal Fat - metabolism Intra-Abdominal Fat - pathology Male Middle Aged Mitochondria - genetics Mitochondria - metabolism Mitochondrial DNA Mitochondrial Proteins - genetics Mitochondrial Proteins - metabolism Real-Time Polymerase Chain Reaction Subcutaneous Fat - metabolism Subcutaneous Fat - pathology
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