Hepatitis E virus isolated from rabbits is genetically heterogeneous but with very similar antigenicity to human HEV

Rabbit hepatitis E virus (HEV) in China may represent a novel HEV genotype, although no consensus has been reached. It is unclear whether the ORF2 capsid protein containing the immunodominant epitopes from rabbit HEV differs from those of human HEV. In this study, 661 bile samples collected from dom...

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Veröffentlicht in:	Journal of medical virology 2013-04, Vol.85 (4), p.627-635
Hauptverfasser:	Wang, Song, Dong, Chen, Dai, Xing, Cheng, Xianfeng, Liang, Jiuhong, Dong, Min, Purdy, Michael A., Meng, Jihong
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigenicity Biological and medical sciences China Cluster Analysis Epitopes - immunology Fundamental and applied biological sciences. Psychology Genotype Genotype & phenotype Hepatitis Hepatitis Antibodies - blood Hepatitis E - veterinary Hepatitis E - virology Hepatitis E virus Hepatitis E virus - classification Hepatitis E virus - genetics Hepatitis E virus - immunology Hepatitis E virus - isolation & purification Human viral diseases Humans Infectious diseases Macaca mulatta Medical sciences Microbiology Miscellaneous Molecular Sequence Data Phylogenetics Phylogeny Proteins rabbit Rabbits Reverse Transcriptase Polymerase Chain Reaction RNA, Viral - genetics Rodent Diseases - virology Sequence Analysis, DNA Serotyping Viral diseases Viral Proteins - genetics Viral Proteins - immunology Virology
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