The Desaturase OPIN17 from Phytophthora infestans Converts Arachidonic Acid to Eicosapentaenoic Acid in CHO Cells

We demonstrate the ability to increase the amount of eicosapentaenoic acid (EPA, 20:5n-3) in mammalian cells using OPIN17 desaturase gene. This gene was codon optimized based on genomic sequence of Δ17 from Phytophthora infestans and introduced into Chinese hamster ovary cells using liposome-mediate...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Applied biochemistry and biotechnology 2013-10, Vol.171 (4), p.975-988
Hauptverfasser:	Fu, Yong, Fan, Xinzhong, Li, Xinzheng, Wang, Hui, Chen, Hongju
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arachidonic Acid - metabolism Biochemistry Biological and medical sciences Biotechnology Cellular biology Chemistry Chemistry and Materials Science CHO Cells Cricetinae Cricetulus Eicosapentaenoic Acid - metabolism Enzymes Fatty Acid Desaturases - metabolism Fundamental and applied biological sciences. Psychology Gene expression Livestock Mammals Microorganisms Phytophthora infestans Phytophthora infestans - enzymology Polyunsaturated fatty acids
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!