Pretreatment with p-aminohippurate inhibits the renal uptake and accumulation of injected inorganic mercury in the rat

The effects of intravenous pretreatment with the organic anion p-aminohippurate (PAH) on the disposition of intravenously administered inorganic mercury in the kidneys, liver and blood were evaluated in rats. In dose-response experiments, the renal uptake (and/or accumulation) of mercury, 1 h after...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Toxicology (Amsterdam) 1995-11, Vol.103 (1), p.23-35
Hauptverfasser:	Zalups, Rudolfs K., Barfuss, Delon W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of Variance Animals Biological and medical sciences Biological Transport, Active Chemical and industrial products toxicology. Toxic occupational diseases Dose-Response Relationship, Drug Feces - chemistry Injections, Intravenous Inorganic mercury Kidney - drug effects Kidney - metabolism Liver - drug effects Liver - metabolism Male Medical sciences Mercuric Chloride - administration & dosage Mercuric Chloride - pharmacokinetics Mercuric Chloride - toxicity Mercury - blood Mercury - metabolism Mercury - urine Metals and various inorganic compounds Organic anion transport system p-Aminohippurate p-Aminohippuric Acid - administration & dosage p-Aminohippuric Acid - pharmacology Rats Rats, Sprague-Dawley Renal uptake Toxicology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!