Determinants of antiretroviral treatment adherence among HIV/AIDS patients: a multisite study
Introduction : Adherence to antiretroviral treatment (ART) is vital in achieving virological treatment success. This study assessed the prevalence of optimal ART adherence and its determinants among HIV/AIDS patients in Vietnam. Method : A cross-sectional survey was conducted with 1,016 HIV/AIDS pat...
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| Veröffentlicht in: | Global health action 2013-12, Vol.6 (1), p.19570-19570 |
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| creator | Xuan Tran, Bach Thanh Nguyen, Long Hoang Nguyen, Nga Van Hoang, Quynh |
| description | Introduction
: Adherence to antiretroviral treatment (ART) is vital in achieving virological treatment success. This study assessed the prevalence of optimal ART adherence and its determinants among HIV/AIDS patients in Vietnam.
Method
: A cross-sectional survey was conducted with 1,016 HIV/AIDS patients at seven hospitals and health centers providing antiretroviral treatment services in three provinces, including Hanoi, Hai Phong, and Ho Chi Minh City. Self-reported medication adherence was measured using a 30-day visual analog scale (VAS) and 7-day missed-doses questions.
Results
: The mean adherence VAS-score was 94.5 out of 100 (SD=8.2), ranging from 40 to 100%. The rate of suboptimal adherence was 25.9%. The rate of missed-doses was 25.2%. In multivariate analysis, increased perceived self-efficacy, use of mobile phone alarms, and reminders from family members were associated with optimal adherence; higher CD4 level, single status, and unstable employment were associated with suboptimal adherence.
Conclusion
: High rate of suboptimal adherence observed in this study highlights the importance of adherence support interventions during ART. The use of mobile phone reminders, involvement of relatives, and HIV self-management training programs have the potential to improve ART adherence in Vietnam. |
| doi_str_mv | 10.3402/gha.v6i0.19570 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_1440219535</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><doaj_id>oai_doaj_org_article_f8f4ec3d47504db7a7fffb63860c11b1</doaj_id><sourcerecordid>1440219535</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5100-cdaacd843bc09e4fd9ace76d95d41a30484f8711f3b5ed9645c1e2fa18cb60443</originalsourceid><addsrcrecordid>eNqNkktvEzEURkcIRB-wZYlGYsMmqT32-MECqWopjVSJBY8dsu74kTiaGQfbE5R_j9O0FUUCsbJlHx_r3vtV1SuM5oSi5my5gvmWeTTHsuXoSXWMWUtnUgj09H7PMTuqTlJaI8QI5-R5ddQQKrls2XH1_dJmGwc_wphTHVxdVh9tjmHrI_R1jhbyYMdcg1nZaEdtaxjCuKyvF9_OzheXn-sNZF-A9K6Gepj67JPPtk55MrsX1TMHfbIv79bT6uvVhy8X17ObTx8XF-c3M91ihGbaAGgjKOk0kpY6I0FbzoxsDcVAEBXUCY6xI11rjWS01dg2DrDQHUOUktNqcfCaAGu1iX6AuFMBvLo9CHGpIGave6uccNRqYihvETUdB-6c6xgRDGmMO1xc7w-uzdQN1uhSWmnEI-njm9Gv1DJsFWEI0aYtgrd3ghh-TDZlNfikbd_DaMOUFKZlcGVc5D9QgrlgmHBW0Dd_oOswxbF0VTUNbhvSCCn-RWHWSEpbwfbfzg-UjiGlaN1DdRipfaxUiZXax0rdxqo8eP17Tx7w-xwVQB4AP7oQB_gZYm9Uhl0fooswap8U-Yv8Fz8L3Tw</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1629445865</pqid></control><display><type>article</type><title>Determinants of antiretroviral treatment adherence among HIV/AIDS patients: a multisite study</title><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>Co-Action Open Access Journals</source><source>Access via Taylor & Francis (Open Access Collection)</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><creator>Xuan Tran, Bach ; Thanh Nguyen, Long ; Hoang Nguyen, Nga ; Van Hoang, Quynh</creator><creatorcontrib>Xuan Tran, Bach ; Thanh Nguyen, Long ; Hoang Nguyen, Nga ; Van Hoang, Quynh</creatorcontrib><description>Introduction
: Adherence to antiretroviral treatment (ART) is vital in achieving virological treatment success. This study assessed the prevalence of optimal ART adherence and its determinants among HIV/AIDS patients in Vietnam.
Method
: A cross-sectional survey was conducted with 1,016 HIV/AIDS patients at seven hospitals and health centers providing antiretroviral treatment services in three provinces, including Hanoi, Hai Phong, and Ho Chi Minh City. Self-reported medication adherence was measured using a 30-day visual analog scale (VAS) and 7-day missed-doses questions.
Results
: The mean adherence VAS-score was 94.5 out of 100 (SD=8.2), ranging from 40 to 100%. The rate of suboptimal adherence was 25.9%. The rate of missed-doses was 25.2%. In multivariate analysis, increased perceived self-efficacy, use of mobile phone alarms, and reminders from family members were associated with optimal adherence; higher CD4 level, single status, and unstable employment were associated with suboptimal adherence.
Conclusion
: High rate of suboptimal adherence observed in this study highlights the importance of adherence support interventions during ART. The use of mobile phone reminders, involvement of relatives, and HIV self-management training programs have the potential to improve ART adherence in Vietnam.</description><identifier>ISSN: 1654-9716</identifier><identifier>ISSN: 1654-9880</identifier><identifier>EISSN: 1654-9880</identifier><identifier>DOI: 10.3402/gha.v6i0.19570</identifier><identifier>PMID: 23497956</identifier><language>eng</language><publisher>United States: Taylor & Francis</publisher><subject>Acquired immune deficiency syndrome ; Acquired Immunodeficiency Syndrome - drug therapy ; Acquired Immunodeficiency Syndrome - psychology ; Adherence ; adherence aid ; Adult ; AIDS ; Anti-Retroviral Agents - administration & dosage ; Anti-Retroviral Agents - therapeutic use ; Antiretroviral agents ; Antiretroviral drugs ; Antiretroviral therapy ; antiretroviral treatment ; CD4 Lymphocyte Count ; Cellular telephones ; Clinical outcomes ; Cross-sectional analysis ; Cross-Sectional Studies ; Dosage ; Drug therapy ; drug users ; Drugs ; Employment ; Female ; Health facilities ; Health services ; HIV ; HIV Infections - drug therapy ; HIV Infections - psychology ; HIV/AIDS ; Hospitals ; Human immunodeficiency virus ; Humans ; Immune response ; Male ; Management development programmes ; Medical treatment ; Medication Adherence ; Mobile phones ; Multivariate analysis ; Original ; Patient compliance ; Patients ; Preventive medicine ; Provinces ; Public health ; Relatives ; Reminder Systems ; Reminders ; Risk Factors ; Self Efficacy ; Self Report ; Selfmanagement ; Socioeconomic Factors ; Vietnam</subject><ispartof>Global health action, 2013-12, Vol.6 (1), p.19570-19570</ispartof><rights>2013 Bach Xuan Tran et al. 2013</rights><rights>Copyright Co-Action Publishing 2013</rights><rights>2013 Bach Xuan Tran et al. This work is licensed under the Creative Commons Attribution – Non-Commercial License http://creativecommons.org/licenses/by-nc/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5100-cdaacd843bc09e4fd9ace76d95d41a30484f8711f3b5ed9645c1e2fa18cb60443</citedby><cites>FETCH-LOGICAL-c5100-cdaacd843bc09e4fd9ace76d95d41a30484f8711f3b5ed9645c1e2fa18cb60443</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600425/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600425/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,315,729,782,786,866,887,2106,4143,27511,27933,27934,53800,53802,59152,59153</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23497956$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Xuan Tran, Bach</creatorcontrib><creatorcontrib>Thanh Nguyen, Long</creatorcontrib><creatorcontrib>Hoang Nguyen, Nga</creatorcontrib><creatorcontrib>Van Hoang, Quynh</creatorcontrib><title>Determinants of antiretroviral treatment adherence among HIV/AIDS patients: a multisite study</title><title>Global health action</title><addtitle>Glob Health Action</addtitle><description>Introduction
: Adherence to antiretroviral treatment (ART) is vital in achieving virological treatment success. This study assessed the prevalence of optimal ART adherence and its determinants among HIV/AIDS patients in Vietnam.
Method
: A cross-sectional survey was conducted with 1,016 HIV/AIDS patients at seven hospitals and health centers providing antiretroviral treatment services in three provinces, including Hanoi, Hai Phong, and Ho Chi Minh City. Self-reported medication adherence was measured using a 30-day visual analog scale (VAS) and 7-day missed-doses questions.
Results
: The mean adherence VAS-score was 94.5 out of 100 (SD=8.2), ranging from 40 to 100%. The rate of suboptimal adherence was 25.9%. The rate of missed-doses was 25.2%. In multivariate analysis, increased perceived self-efficacy, use of mobile phone alarms, and reminders from family members were associated with optimal adherence; higher CD4 level, single status, and unstable employment were associated with suboptimal adherence.
Conclusion
: High rate of suboptimal adherence observed in this study highlights the importance of adherence support interventions during ART. The use of mobile phone reminders, involvement of relatives, and HIV self-management training programs have the potential to improve ART adherence in Vietnam.</description><subject>Acquired immune deficiency syndrome</subject><subject>Acquired Immunodeficiency Syndrome - drug therapy</subject><subject>Acquired Immunodeficiency Syndrome - psychology</subject><subject>Adherence</subject><subject>adherence aid</subject><subject>Adult</subject><subject>AIDS</subject><subject>Anti-Retroviral Agents - administration & dosage</subject><subject>Anti-Retroviral Agents - therapeutic use</subject><subject>Antiretroviral agents</subject><subject>Antiretroviral drugs</subject><subject>Antiretroviral therapy</subject><subject>antiretroviral treatment</subject><subject>CD4 Lymphocyte Count</subject><subject>Cellular telephones</subject><subject>Clinical outcomes</subject><subject>Cross-sectional analysis</subject><subject>Cross-Sectional Studies</subject><subject>Dosage</subject><subject>Drug therapy</subject><subject>drug users</subject><subject>Drugs</subject><subject>Employment</subject><subject>Female</subject><subject>Health facilities</subject><subject>Health services</subject><subject>HIV</subject><subject>HIV Infections - drug therapy</subject><subject>HIV Infections - psychology</subject><subject>HIV/AIDS</subject><subject>Hospitals</subject><subject>Human immunodeficiency virus</subject><subject>Humans</subject><subject>Immune response</subject><subject>Male</subject><subject>Management development programmes</subject><subject>Medical treatment</subject><subject>Medication Adherence</subject><subject>Mobile phones</subject><subject>Multivariate analysis</subject><subject>Original</subject><subject>Patient compliance</subject><subject>Patients</subject><subject>Preventive medicine</subject><subject>Provinces</subject><subject>Public health</subject><subject>Relatives</subject><subject>Reminder Systems</subject><subject>Reminders</subject><subject>Risk Factors</subject><subject>Self Efficacy</subject><subject>Self Report</subject><subject>Selfmanagement</subject><subject>Socioeconomic Factors</subject><subject>Vietnam</subject><issn>1654-9716</issn><issn>1654-9880</issn><issn>1654-9880</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>0YH</sourceid><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><sourceid>DOA</sourceid><recordid>eNqNkktvEzEURkcIRB-wZYlGYsMmqT32-MECqWopjVSJBY8dsu74kTiaGQfbE5R_j9O0FUUCsbJlHx_r3vtV1SuM5oSi5my5gvmWeTTHsuXoSXWMWUtnUgj09H7PMTuqTlJaI8QI5-R5ddQQKrls2XH1_dJmGwc_wphTHVxdVh9tjmHrI_R1jhbyYMdcg1nZaEdtaxjCuKyvF9_OzheXn-sNZF-A9K6Gepj67JPPtk55MrsX1TMHfbIv79bT6uvVhy8X17ObTx8XF-c3M91ihGbaAGgjKOk0kpY6I0FbzoxsDcVAEBXUCY6xI11rjWS01dg2DrDQHUOUktNqcfCaAGu1iX6AuFMBvLo9CHGpIGave6uccNRqYihvETUdB-6c6xgRDGmMO1xc7w-uzdQN1uhSWmnEI-njm9Gv1DJsFWEI0aYtgrd3ghh-TDZlNfikbd_DaMOUFKZlcGVc5D9QgrlgmHBW0Dd_oOswxbF0VTUNbhvSCCn-RWHWSEpbwfbfzg-UjiGlaN1DdRipfaxUiZXax0rdxqo8eP17Tx7w-xwVQB4AP7oQB_gZYm9Uhl0fooswap8U-Yv8Fz8L3Tw</recordid><startdate>20131201</startdate><enddate>20131201</enddate><creator>Xuan Tran, Bach</creator><creator>Thanh Nguyen, Long</creator><creator>Hoang Nguyen, Nga</creator><creator>Van Hoang, Quynh</creator><general>Taylor & Francis</general><general>Taylor & Francis Ltd</general><general>Co-Action Publishing</general><general>Taylor & Francis Group</general><scope>0YH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8BJ</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FQK</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>JBE</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20131201</creationdate><title>Determinants of antiretroviral treatment adherence among HIV/AIDS patients: a multisite study</title><author>Xuan Tran, Bach ; Thanh Nguyen, Long ; Hoang Nguyen, Nga ; Van Hoang, Quynh</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5100-cdaacd843bc09e4fd9ace76d95d41a30484f8711f3b5ed9645c1e2fa18cb60443</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Acquired immune deficiency syndrome</topic><topic>Acquired Immunodeficiency Syndrome - drug therapy</topic><topic>Acquired Immunodeficiency Syndrome - psychology</topic><topic>Adherence</topic><topic>adherence aid</topic><topic>Adult</topic><topic>AIDS</topic><topic>Anti-Retroviral Agents - administration & dosage</topic><topic>Anti-Retroviral Agents - therapeutic use</topic><topic>Antiretroviral agents</topic><topic>Antiretroviral drugs</topic><topic>Antiretroviral therapy</topic><topic>antiretroviral treatment</topic><topic>CD4 Lymphocyte Count</topic><topic>Cellular telephones</topic><topic>Clinical outcomes</topic><topic>Cross-sectional analysis</topic><topic>Cross-Sectional Studies</topic><topic>Dosage</topic><topic>Drug therapy</topic><topic>drug users</topic><topic>Drugs</topic><topic>Employment</topic><topic>Female</topic><topic>Health facilities</topic><topic>Health services</topic><topic>HIV</topic><topic>HIV Infections - drug therapy</topic><topic>HIV Infections - psychology</topic><topic>HIV/AIDS</topic><topic>Hospitals</topic><topic>Human immunodeficiency virus</topic><topic>Humans</topic><topic>Immune response</topic><topic>Male</topic><topic>Management development programmes</topic><topic>Medical treatment</topic><topic>Medication Adherence</topic><topic>Mobile phones</topic><topic>Multivariate analysis</topic><topic>Original</topic><topic>Patient compliance</topic><topic>Patients</topic><topic>Preventive medicine</topic><topic>Provinces</topic><topic>Public health</topic><topic>Relatives</topic><topic>Reminder Systems</topic><topic>Reminders</topic><topic>Risk Factors</topic><topic>Self Efficacy</topic><topic>Self Report</topic><topic>Selfmanagement</topic><topic>Socioeconomic Factors</topic><topic>Vietnam</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Xuan Tran, Bach</creatorcontrib><creatorcontrib>Thanh Nguyen, Long</creatorcontrib><creatorcontrib>Hoang Nguyen, Nga</creatorcontrib><creatorcontrib>Van Hoang, Quynh</creatorcontrib><collection>Access via Taylor & Francis (Open Access Collection)</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>International Bibliography of the Social Sciences (IBSS)</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>International Bibliography of the Social Sciences</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>International Bibliography of the Social Sciences</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Access via ProQuest (Open Access)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Global health action</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Xuan Tran, Bach</au><au>Thanh Nguyen, Long</au><au>Hoang Nguyen, Nga</au><au>Van Hoang, Quynh</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Determinants of antiretroviral treatment adherence among HIV/AIDS patients: a multisite study</atitle><jtitle>Global health action</jtitle><addtitle>Glob Health Action</addtitle><date>2013-12-01</date><risdate>2013</risdate><volume>6</volume><issue>1</issue><spage>19570</spage><epage>19570</epage><pages>19570-19570</pages><issn>1654-9716</issn><issn>1654-9880</issn><eissn>1654-9880</eissn><abstract>Introduction
: Adherence to antiretroviral treatment (ART) is vital in achieving virological treatment success. This study assessed the prevalence of optimal ART adherence and its determinants among HIV/AIDS patients in Vietnam.
Method
: A cross-sectional survey was conducted with 1,016 HIV/AIDS patients at seven hospitals and health centers providing antiretroviral treatment services in three provinces, including Hanoi, Hai Phong, and Ho Chi Minh City. Self-reported medication adherence was measured using a 30-day visual analog scale (VAS) and 7-day missed-doses questions.
Results
: The mean adherence VAS-score was 94.5 out of 100 (SD=8.2), ranging from 40 to 100%. The rate of suboptimal adherence was 25.9%. The rate of missed-doses was 25.2%. In multivariate analysis, increased perceived self-efficacy, use of mobile phone alarms, and reminders from family members were associated with optimal adherence; higher CD4 level, single status, and unstable employment were associated with suboptimal adherence.
Conclusion
: High rate of suboptimal adherence observed in this study highlights the importance of adherence support interventions during ART. The use of mobile phone reminders, involvement of relatives, and HIV self-management training programs have the potential to improve ART adherence in Vietnam.</abstract><cop>United States</cop><pub>Taylor & Francis</pub><pmid>23497956</pmid><doi>10.3402/gha.v6i0.19570</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Acquired immune deficiency syndrome Acquired Immunodeficiency Syndrome - drug therapy Acquired Immunodeficiency Syndrome - psychology Adherence adherence aid Adult AIDS Anti-Retroviral Agents - administration & dosage Anti-Retroviral Agents - therapeutic use Antiretroviral agents Antiretroviral drugs Antiretroviral therapy antiretroviral treatment CD4 Lymphocyte Count Cellular telephones Clinical outcomes Cross-sectional analysis Cross-Sectional Studies Dosage Drug therapy drug users Drugs Employment Female Health facilities Health services HIV HIV Infections - drug therapy HIV Infections - psychology HIV/AIDS Hospitals Human immunodeficiency virus Humans Immune response Male Management development programmes Medical treatment Medication Adherence Mobile phones Multivariate analysis Original Patient compliance Patients Preventive medicine Provinces Public health Relatives Reminder Systems Reminders Risk Factors Self Efficacy Self Report Selfmanagement Socioeconomic Factors Vietnam |
| title | Determinants of antiretroviral treatment adherence among HIV/AIDS patients: a multisite study |
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