Clay: New Opportunities for Tissue Regeneration and Biomaterial Design
Seminal recent studies that have shed new light on the remarkable properties of clay interactions suggest unexplored opportunities for biomaterial design and regenerative medicine. Here, recent conceptual and technological developments in the science of clay interactions with biomolecules, polymers,...
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Veröffentlicht in: | Advanced materials (Weinheim) 2013-08, Vol.25 (30), p.4069-4086 |
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creator | Dawson, Jonathan I. Oreffo, Richard O. C. |
description | Seminal recent studies that have shed new light on the remarkable properties of clay interactions suggest unexplored opportunities for biomaterial design and regenerative medicine. Here, recent conceptual and technological developments in the science of clay interactions with biomolecules, polymers, and cells are examined, focusing on the implications for tissue engineering and regenerative strategies. Pioneering studies demonstrating the utility of clay for drug‐delivery and scaffold design are reviewed and areas for future research and development highlighted.
Harnessing clay interactions for tissue regeneration: clay nanoparticles interact with biomolecules to allow controlled delivery, with polymers to give tough materials, and with cells to mediate adhesion and proliferation. The unexplored opportunities that clay minerals present for tissue engineering and regenerative medicine are highlighted. |
doi_str_mv | 10.1002/adma.201301034 |
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Harnessing clay interactions for tissue regeneration: clay nanoparticles interact with biomolecules to allow controlled delivery, with polymers to give tough materials, and with cells to mediate adhesion and proliferation. The unexplored opportunities that clay minerals present for tissue engineering and regenerative medicine are highlighted.</description><subject>Aluminum Silicates - chemical synthesis</subject><subject>Biocompatible Materials - chemical synthesis</subject><subject>Biomaterials</subject><subject>Biomedical materials</subject><subject>Biomolecules</subject><subject>Clay (material)</subject><subject>clay materials</subject><subject>Clay minerals</subject><subject>Drug Carriers - chemical synthesis</subject><subject>drug delivery</subject><subject>Equipment Design - trends</subject><subject>Guided Tissue Regeneration - instrumentation</subject><subject>Guided Tissue Regeneration - trends</subject><subject>nanocomposites</subject><subject>nanoparticles</subject><subject>Regeneration</subject><subject>Regenerative</subject><subject>Surgical implants</subject><subject>Tissue Engineering - instrumentation</subject><subject>Tissue Engineering - trends</subject><subject>tissue regeneration</subject><subject>Tissue Scaffolds - trends</subject><issn>0935-9648</issn><issn>1521-4095</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkDtPG0EURkdRUDAkbcpoyzRr7rx30hmbBcRLikhSjmY9d9HAPszMrsD_HiODlY7qa853ikPIdwpTCsCOnG_dlAHlQIGLT2RCJaO5ACM_kwkYLnOjRLFPDlK6BwCjQH0h-4xrxjijE1LOG7f-lV3jU3azWvVxGLswBExZ3cfsNqQ0YvYb77DD6IbQd5nrfHYc-tYNGINrsgWmcNd9JXu1axJ-e9tD8qc8uZ2f5Zc3p-fz2WW-lIyJXJmKgoJK1wWnDLX30ulKeylRaFUbVmhhCg1ee1ErWfCCayWgAu6XznHgh-Tn1ruK_eOIabBtSEtsGtdhPyZLBTdaMVYUG3S6RZexTylibVcxtC6uLQX72s6-trO7dpvDjzf3WLXod_h7rA1gtsBTaHD9gc7OFlez_-X59hvSgM-7r4sPVmmupf13fWqPL8qSLf4aW_IXm6mIOg</recordid><startdate>20130814</startdate><enddate>20130814</enddate><creator>Dawson, Jonathan I.</creator><creator>Oreffo, Richard O. 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C.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Engineered Materials Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><jtitle>Advanced materials (Weinheim)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dawson, Jonathan I.</au><au>Oreffo, Richard O. C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clay: New Opportunities for Tissue Regeneration and Biomaterial Design</atitle><jtitle>Advanced materials (Weinheim)</jtitle><addtitle>Adv. Mater</addtitle><date>2013-08-14</date><risdate>2013</risdate><volume>25</volume><issue>30</issue><spage>4069</spage><epage>4086</epage><pages>4069-4086</pages><issn>0935-9648</issn><eissn>1521-4095</eissn><abstract>Seminal recent studies that have shed new light on the remarkable properties of clay interactions suggest unexplored opportunities for biomaterial design and regenerative medicine. Here, recent conceptual and technological developments in the science of clay interactions with biomolecules, polymers, and cells are examined, focusing on the implications for tissue engineering and regenerative strategies. Pioneering studies demonstrating the utility of clay for drug‐delivery and scaffold design are reviewed and areas for future research and development highlighted.
Harnessing clay interactions for tissue regeneration: clay nanoparticles interact with biomolecules to allow controlled delivery, with polymers to give tough materials, and with cells to mediate adhesion and proliferation. The unexplored opportunities that clay minerals present for tissue engineering and regenerative medicine are highlighted.</abstract><cop>Weinheim</cop><pub>WILEY-VCH Verlag</pub><pmid>23722321</pmid><doi>10.1002/adma.201301034</doi><tpages>18</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Aluminum Silicates - chemical synthesis Biocompatible Materials - chemical synthesis Biomaterials Biomedical materials Biomolecules Clay (material) clay materials Clay minerals Drug Carriers - chemical synthesis drug delivery Equipment Design - trends Guided Tissue Regeneration - instrumentation Guided Tissue Regeneration - trends nanocomposites nanoparticles Regeneration Regenerative Surgical implants Tissue Engineering - instrumentation Tissue Engineering - trends tissue regeneration Tissue Scaffolds - trends |
title | Clay: New Opportunities for Tissue Regeneration and Biomaterial Design |
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