Clay: New Opportunities for Tissue Regeneration and Biomaterial Design

Seminal recent studies that have shed new light on the remarkable properties of clay interactions suggest unexplored opportunities for biomaterial design and regenerative medicine. Here, recent conceptual and technological developments in the science of clay interactions with biomolecules, polymers,...

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Veröffentlicht in:Advanced materials (Weinheim) 2013-08, Vol.25 (30), p.4069-4086
Hauptverfasser: Dawson, Jonathan I., Oreffo, Richard O. C.
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Oreffo, Richard O. C.
description Seminal recent studies that have shed new light on the remarkable properties of clay interactions suggest unexplored opportunities for biomaterial design and regenerative medicine. Here, recent conceptual and technological developments in the science of clay interactions with biomolecules, polymers, and cells are examined, focusing on the implications for tissue engineering and regenerative strategies. Pioneering studies demonstrating the utility of clay for drug‐delivery and scaffold design are reviewed and areas for future research and development highlighted. Harnessing clay interactions for tissue regeneration: clay nanoparticles interact with biomolecules to allow controlled delivery, with polymers to give tough materials, and with cells to mediate adhesion and proliferation. The unexplored opportunities that clay minerals present for tissue engineering and regenerative medicine are highlighted.
doi_str_mv 10.1002/adma.201301034
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subjects Aluminum Silicates - chemical synthesis
Biocompatible Materials - chemical synthesis
Biomaterials
Biomedical materials
Biomolecules
Clay (material)
clay materials
Clay minerals
Drug Carriers - chemical synthesis
drug delivery
Equipment Design - trends
Guided Tissue Regeneration - instrumentation
Guided Tissue Regeneration - trends
nanocomposites
nanoparticles
Regeneration
Regenerative
Surgical implants
Tissue Engineering - instrumentation
Tissue Engineering - trends
tissue regeneration
Tissue Scaffolds - trends
title Clay: New Opportunities for Tissue Regeneration and Biomaterial Design
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