Magnetic Hydrogels and Their Potential Biomedical Applications
Hydrogels find widespread applications in biomedical engineering due to their hydrated environment and tunable properties (e.g., mechanical, chemical, biocompatible) similar to the native extracellular matrix (ECM). However, challenges still exist regarding utilizing hydrogels in applications such a...
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| Veröffentlicht in: | Advanced functional materials 2013-02, Vol.23 (6), p.660-672 |
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| container_end_page | 672 |
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| container_issue | 6 |
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| container_title | Advanced functional materials |
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| creator | Li, Yuhui Huang, Guoyou Zhang, Xiaohui Li, Baoqiang Chen, Yongmei Lu, Tingli Lu, Tian Jian Xu, Feng |
| description | Hydrogels find widespread applications in biomedical engineering due to their hydrated environment and tunable properties (e.g., mechanical, chemical, biocompatible) similar to the native extracellular matrix (ECM). However, challenges still exist regarding utilizing hydrogels in applications such as engineering 3D tissue constructs and active targeting in drug delivery, due to the lack of controllability, actuation, and quick‐response properties. Recently, magnetic hydrogels have emerged as a novel biocomposite for their active response properties and extended applications. In this review, the state‐of‐the‐art methods for magnetic hydrogel preparation are presented and their advantages and drawbacks in applications are discussed. The applications of magnetic hydrogels in biomedical engineering are also reviewed, including tissue engineering, drug delivery and release, enzyme immobilization, cancer therapy, and soft actuators. Concluding remarks and perspectives for the future development of magnetic hydrogels are addressed.
Magnetic hydrogels are emerging as a novel biocomposite for active response properties and extended applications. State‐of‐the‐art methods for magnetic hydrogel fabrication are presented. The applications of magnetic hydrogels in biomedical engineering are also reviewed, including tissue engineering, drug delivery and enzyme immobilization, cancer therapy, and soft actuators. Concluding remarks and perspectives for the future development of magnetic hydrogels are addressed. |
| doi_str_mv | 10.1002/adfm.201201708 |
| format | Article |
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Magnetic hydrogels are emerging as a novel biocomposite for active response properties and extended applications. State‐of‐the‐art methods for magnetic hydrogel fabrication are presented. The applications of magnetic hydrogels in biomedical engineering are also reviewed, including tissue engineering, drug delivery and enzyme immobilization, cancer therapy, and soft actuators. Concluding remarks and perspectives for the future development of magnetic hydrogels are addressed.</description><identifier>ISSN: 1616-301X</identifier><identifier>EISSN: 1616-3028</identifier><identifier>DOI: 10.1002/adfm.201201708</identifier><language>eng</language><publisher>Weinheim: WILEY-VCH Verlag</publisher><subject>Active control ; Biomedical engineering ; controllability ; Drug delivery systems ; Enzymes ; Hydrogels ; Immobilization ; magnetic hydrogels ; magnetic nanoparticles (MNPs) ; response properties ; State of the art ; Therapy</subject><ispartof>Advanced functional materials, 2013-02, Vol.23 (6), p.660-672</ispartof><rights>Copyright © 2013 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3978-7be706ac8047af23d1704668b64bbed651865ef1571fd021121b01858a90fed43</citedby><cites>FETCH-LOGICAL-c3978-7be706ac8047af23d1704668b64bbed651865ef1571fd021121b01858a90fed43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fadfm.201201708$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fadfm.201201708$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids></links><search><creatorcontrib>Li, Yuhui</creatorcontrib><creatorcontrib>Huang, Guoyou</creatorcontrib><creatorcontrib>Zhang, Xiaohui</creatorcontrib><creatorcontrib>Li, Baoqiang</creatorcontrib><creatorcontrib>Chen, Yongmei</creatorcontrib><creatorcontrib>Lu, Tingli</creatorcontrib><creatorcontrib>Lu, Tian Jian</creatorcontrib><creatorcontrib>Xu, Feng</creatorcontrib><title>Magnetic Hydrogels and Their Potential Biomedical Applications</title><title>Advanced functional materials</title><addtitle>Adv. Funct. Mater</addtitle><description>Hydrogels find widespread applications in biomedical engineering due to their hydrated environment and tunable properties (e.g., mechanical, chemical, biocompatible) similar to the native extracellular matrix (ECM). However, challenges still exist regarding utilizing hydrogels in applications such as engineering 3D tissue constructs and active targeting in drug delivery, due to the lack of controllability, actuation, and quick‐response properties. Recently, magnetic hydrogels have emerged as a novel biocomposite for their active response properties and extended applications. In this review, the state‐of‐the‐art methods for magnetic hydrogel preparation are presented and their advantages and drawbacks in applications are discussed. The applications of magnetic hydrogels in biomedical engineering are also reviewed, including tissue engineering, drug delivery and release, enzyme immobilization, cancer therapy, and soft actuators. Concluding remarks and perspectives for the future development of magnetic hydrogels are addressed.
Magnetic hydrogels are emerging as a novel biocomposite for active response properties and extended applications. State‐of‐the‐art methods for magnetic hydrogel fabrication are presented. The applications of magnetic hydrogels in biomedical engineering are also reviewed, including tissue engineering, drug delivery and enzyme immobilization, cancer therapy, and soft actuators. Concluding remarks and perspectives for the future development of magnetic hydrogels are addressed.</description><subject>Active control</subject><subject>Biomedical engineering</subject><subject>controllability</subject><subject>Drug delivery systems</subject><subject>Enzymes</subject><subject>Hydrogels</subject><subject>Immobilization</subject><subject>magnetic hydrogels</subject><subject>magnetic nanoparticles (MNPs)</subject><subject>response properties</subject><subject>State of the art</subject><subject>Therapy</subject><issn>1616-301X</issn><issn>1616-3028</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><recordid>eNqFkDtPwzAURi0EEqWwMmdkSfEjsZ0FqRTaIrXAUEQ3y0luiiEv7FTQf4-roIoNydL9hnOurz6ELgkeEYzptc6LakQx8U9geYQGhBMeMkzl8SGT9Sk6c-4de0awaIBulnpTQ2eyYL7LbbOB0gW6zoPVGxgbPDcd1J3RZXBrmgpyk_k4btvSh840tTtHJ4UuHVz8ziF6md6vJvNw8TR7mIwXYcYSIUORgsBcZxJHQheU5f7CiHOZ8ihNIecxkTyGgsSCFDmmhFCSYiJjqRNcQB6xIbrq97a2-dyC61RlXAZlqWtotk6RyP8TC8aoR0c9mtnGOQuFaq2ptN0pgtW-KLUvSh2K8kLSC1-mhN0_tBrfTZd_3bB3jevg--Bq-6G4YCJWr48zxRM6Wd-JtVqyH6-Tens</recordid><startdate>20130211</startdate><enddate>20130211</enddate><creator>Li, Yuhui</creator><creator>Huang, Guoyou</creator><creator>Zhang, Xiaohui</creator><creator>Li, Baoqiang</creator><creator>Chen, Yongmei</creator><creator>Lu, Tingli</creator><creator>Lu, Tian Jian</creator><creator>Xu, Feng</creator><general>WILEY-VCH Verlag</general><general>WILEY‐VCH Verlag</general><scope>BSCLL</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SP</scope><scope>7SR</scope><scope>7U5</scope><scope>8BQ</scope><scope>8FD</scope><scope>JG9</scope><scope>L7M</scope></search><sort><creationdate>20130211</creationdate><title>Magnetic Hydrogels and Their Potential Biomedical Applications</title><author>Li, Yuhui ; Huang, Guoyou ; Zhang, Xiaohui ; Li, Baoqiang ; Chen, Yongmei ; Lu, Tingli ; Lu, Tian Jian ; Xu, Feng</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3978-7be706ac8047af23d1704668b64bbed651865ef1571fd021121b01858a90fed43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Active control</topic><topic>Biomedical engineering</topic><topic>controllability</topic><topic>Drug delivery systems</topic><topic>Enzymes</topic><topic>Hydrogels</topic><topic>Immobilization</topic><topic>magnetic hydrogels</topic><topic>magnetic nanoparticles (MNPs)</topic><topic>response properties</topic><topic>State of the art</topic><topic>Therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Li, Yuhui</creatorcontrib><creatorcontrib>Huang, Guoyou</creatorcontrib><creatorcontrib>Zhang, Xiaohui</creatorcontrib><creatorcontrib>Li, Baoqiang</creatorcontrib><creatorcontrib>Chen, Yongmei</creatorcontrib><creatorcontrib>Lu, Tingli</creatorcontrib><creatorcontrib>Lu, Tian Jian</creatorcontrib><creatorcontrib>Xu, Feng</creatorcontrib><collection>Istex</collection><collection>CrossRef</collection><collection>Electronics & Communications Abstracts</collection><collection>Engineered Materials Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><jtitle>Advanced functional materials</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Li, Yuhui</au><au>Huang, Guoyou</au><au>Zhang, Xiaohui</au><au>Li, Baoqiang</au><au>Chen, Yongmei</au><au>Lu, Tingli</au><au>Lu, Tian Jian</au><au>Xu, Feng</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Magnetic Hydrogels and Their Potential Biomedical Applications</atitle><jtitle>Advanced functional materials</jtitle><addtitle>Adv. Funct. Mater</addtitle><date>2013-02-11</date><risdate>2013</risdate><volume>23</volume><issue>6</issue><spage>660</spage><epage>672</epage><pages>660-672</pages><issn>1616-301X</issn><eissn>1616-3028</eissn><abstract>Hydrogels find widespread applications in biomedical engineering due to their hydrated environment and tunable properties (e.g., mechanical, chemical, biocompatible) similar to the native extracellular matrix (ECM). However, challenges still exist regarding utilizing hydrogels in applications such as engineering 3D tissue constructs and active targeting in drug delivery, due to the lack of controllability, actuation, and quick‐response properties. Recently, magnetic hydrogels have emerged as a novel biocomposite for their active response properties and extended applications. In this review, the state‐of‐the‐art methods for magnetic hydrogel preparation are presented and their advantages and drawbacks in applications are discussed. The applications of magnetic hydrogels in biomedical engineering are also reviewed, including tissue engineering, drug delivery and release, enzyme immobilization, cancer therapy, and soft actuators. Concluding remarks and perspectives for the future development of magnetic hydrogels are addressed.
Magnetic hydrogels are emerging as a novel biocomposite for active response properties and extended applications. State‐of‐the‐art methods for magnetic hydrogel fabrication are presented. The applications of magnetic hydrogels in biomedical engineering are also reviewed, including tissue engineering, drug delivery and enzyme immobilization, cancer therapy, and soft actuators. Concluding remarks and perspectives for the future development of magnetic hydrogels are addressed.</abstract><cop>Weinheim</cop><pub>WILEY-VCH Verlag</pub><doi>10.1002/adfm.201201708</doi><tpages>13</tpages></addata></record> |
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| ispartof | Advanced functional materials, 2013-02, Vol.23 (6), p.660-672 |
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| language | eng |
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| source | Wiley Online Library Journals Frontfile Complete |
| subjects | Active control Biomedical engineering controllability Drug delivery systems Enzymes Hydrogels Immobilization magnetic hydrogels magnetic nanoparticles (MNPs) response properties State of the art Therapy |
| title | Magnetic Hydrogels and Their Potential Biomedical Applications |
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