Evaluation of thermal stability and parameters of dissolution of nifedipine crystals

Nifedipine is a calcium channel blocker as well as a powerful vasodilator used to treat ischemic heart disease and hypertension. Its photosensitivity and very low solubility in water have been widely acknowledged as important properties deserving improvements. The main thrust of this study is to cha...

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Veröffentlicht in:	Journal of thermal analysis and calorimetry 2013-03, Vol.111 (3), p.2117-2123
Hauptverfasser:	Da Silva Leite, Renata, De Oliveira Macedo, Rui, Torres, Sandro Marden, Batista, Caio Cesar Neves, De Oliveira Baltazar, Lays, Neto, Severino Antônio Lima, De Souza, Fábio Santos
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical Chemistry Biological and medical sciences Calcium channels Cardiovascular system Chemical properties Chemistry Chemistry and Materials Science Crystal structure Crystals Dissolution General pharmacology Hypertension Inorganic Chemistry Ischemia Mathematical models Measurement Science and Instrumentation Medical sciences Miscellaneous Nifedipine Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Physical Chemistry Polymer Sciences Reaction kinetics Solubility Structure Thermal stability
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