Novel atmospheric plasma enhanced chitosan nanofiber/gauze composite wound dressings
Electrospun chitosan nanofibers were deposited onto atmospheric plasma treated cotton gauze to create a novel composite bandage with higher adhesion, better handling properties, enhanced bioactivity, and moisture management. Plasma treatment of the gauze substrate was performed to improve the durabi...
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| Veröffentlicht in: | Journal of applied polymer science 2013-07, Vol.129 (2), p.916-923 |
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| container_title | Journal of applied polymer science |
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| creator | Nawalakhe, Rupesh Shi, Quan Vitchuli, Narendiran Noar, Jesse Caldwell, Jane M. Breidt, Frederick Bourham, Mohamed A. Zhang, Xiangwu McCord, Marian G. |
| description | Electrospun chitosan nanofibers were deposited onto atmospheric plasma treated cotton gauze to create a novel composite bandage with higher adhesion, better handling properties, enhanced bioactivity, and moisture management. Plasma treatment of the gauze substrate was performed to improve the durability of the nanofiber/gauze interface. The chitosan nanofibers were electrospun at 3–7% concentration in trifluoroacetic acid. The composite bandages were analyzed using peel, gelbo flex, antimicrobial assay, moisture vapor transmission rate, X‐ray photoelectron spectroscopy (XPS), absorbency, and air permeability tests. The peel test showed that plasma treatment of the substrate increased the adhesion between nanofiber layers and gauze substrate by up to four times. Atmospheric plasma pretreatment of the gauze fabric prior to electrospinning significantly reduced degradation of the nanofiber layer due to repetitive flexing. The chitosan nanofiber layer contributes significantly to the antimicrobial properties of the bandage. Air permeability and moisture vapor transport were reduced due to the presence of a nanofiber layer upon the substrate. XPS of the plasma treated cotton substrate showed formation of active sites on the surface, decrease in carbon content, and increase in oxygen content as compared to the untreated gauze. Deposition of chitosan nanofibers also increased the absorbency of gauze substrate. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013 |
| doi_str_mv | 10.1002/app.38804 |
| format | Article |
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Plasma treatment of the gauze substrate was performed to improve the durability of the nanofiber/gauze interface. The chitosan nanofibers were electrospun at 3–7% concentration in trifluoroacetic acid. The composite bandages were analyzed using peel, gelbo flex, antimicrobial assay, moisture vapor transmission rate, X‐ray photoelectron spectroscopy (XPS), absorbency, and air permeability tests. The peel test showed that plasma treatment of the substrate increased the adhesion between nanofiber layers and gauze substrate by up to four times. Atmospheric plasma pretreatment of the gauze fabric prior to electrospinning significantly reduced degradation of the nanofiber layer due to repetitive flexing. The chitosan nanofiber layer contributes significantly to the antimicrobial properties of the bandage. Air permeability and moisture vapor transport were reduced due to the presence of a nanofiber layer upon the substrate. XPS of the plasma treated cotton substrate showed formation of active sites on the surface, decrease in carbon content, and increase in oxygen content as compared to the untreated gauze. Deposition of chitosan nanofibers also increased the absorbency of gauze substrate. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013</description><identifier>ISSN: 0021-8995</identifier><identifier>ISSN: 1097-4628</identifier><identifier>EISSN: 1097-4628</identifier><identifier>DOI: 10.1002/app.38804</identifier><identifier>CODEN: JAPNAB</identifier><language>eng</language><publisher>Hoboken: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>absorbance ; active sites ; adhesion ; air ; antimicrobial properties ; Atmospherics ; bandages ; biomedical applications ; biopolymers and renewable polymers ; carbon ; Chitosan ; composite materials ; composites ; cotton ; durability ; Electrospinning ; fabrics ; Gauze ; Materials science ; Nanocomposites ; nanofibers ; Nanomaterials ; Nanostructure ; nanostructured polymers ; organofluorine compounds ; oxygen ; permeability ; Polymers ; tissue repair ; vapors ; X-ray photoelectron spectroscopy</subject><ispartof>Journal of applied polymer science, 2013-07, Vol.129 (2), p.916-923</ispartof><rights>Copyright © 2013 Wiley Periodicals, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4014-feea984afdcfa4c4e14bc36c21fb10e655d0ecf16bddeff4469f2e3d6ad104df3</citedby><cites>FETCH-LOGICAL-c4014-feea984afdcfa4c4e14bc36c21fb10e655d0ecf16bddeff4469f2e3d6ad104df3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fapp.38804$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fapp.38804$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids></links><search><creatorcontrib>Nawalakhe, Rupesh</creatorcontrib><creatorcontrib>Shi, Quan</creatorcontrib><creatorcontrib>Vitchuli, Narendiran</creatorcontrib><creatorcontrib>Noar, Jesse</creatorcontrib><creatorcontrib>Caldwell, Jane M.</creatorcontrib><creatorcontrib>Breidt, Frederick</creatorcontrib><creatorcontrib>Bourham, Mohamed A.</creatorcontrib><creatorcontrib>Zhang, Xiangwu</creatorcontrib><creatorcontrib>McCord, Marian G.</creatorcontrib><title>Novel atmospheric plasma enhanced chitosan nanofiber/gauze composite wound dressings</title><title>Journal of applied polymer science</title><addtitle>J. Appl. Polym. Sci</addtitle><description>Electrospun chitosan nanofibers were deposited onto atmospheric plasma treated cotton gauze to create a novel composite bandage with higher adhesion, better handling properties, enhanced bioactivity, and moisture management. Plasma treatment of the gauze substrate was performed to improve the durability of the nanofiber/gauze interface. The chitosan nanofibers were electrospun at 3–7% concentration in trifluoroacetic acid. The composite bandages were analyzed using peel, gelbo flex, antimicrobial assay, moisture vapor transmission rate, X‐ray photoelectron spectroscopy (XPS), absorbency, and air permeability tests. The peel test showed that plasma treatment of the substrate increased the adhesion between nanofiber layers and gauze substrate by up to four times. Atmospheric plasma pretreatment of the gauze fabric prior to electrospinning significantly reduced degradation of the nanofiber layer due to repetitive flexing. The chitosan nanofiber layer contributes significantly to the antimicrobial properties of the bandage. Air permeability and moisture vapor transport were reduced due to the presence of a nanofiber layer upon the substrate. XPS of the plasma treated cotton substrate showed formation of active sites on the surface, decrease in carbon content, and increase in oxygen content as compared to the untreated gauze. Deposition of chitosan nanofibers also increased the absorbency of gauze substrate. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013</description><subject>absorbance</subject><subject>active sites</subject><subject>adhesion</subject><subject>air</subject><subject>antimicrobial properties</subject><subject>Atmospherics</subject><subject>bandages</subject><subject>biomedical applications</subject><subject>biopolymers and renewable polymers</subject><subject>carbon</subject><subject>Chitosan</subject><subject>composite materials</subject><subject>composites</subject><subject>cotton</subject><subject>durability</subject><subject>Electrospinning</subject><subject>fabrics</subject><subject>Gauze</subject><subject>Materials science</subject><subject>Nanocomposites</subject><subject>nanofibers</subject><subject>Nanomaterials</subject><subject>Nanostructure</subject><subject>nanostructured polymers</subject><subject>organofluorine compounds</subject><subject>oxygen</subject><subject>permeability</subject><subject>Polymers</subject><subject>tissue repair</subject><subject>vapors</subject><subject>X-ray photoelectron spectroscopy</subject><issn>0021-8995</issn><issn>1097-4628</issn><issn>1097-4628</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><recordid>eNqF0UFv0zAUB3ALDYlucOAbROLCDlnt2HHs4zZYN6kaPRQhcbFc-7n1SOzMTijj05OtwGES4vQO7_d_0tMfobcEnxGMq7nu-zMqBGYv0Ixg2ZSMV-IIzaYdKYWU9St0nPMdxoTUmM_Q-jZ-h7bQQxdzv4PkTdG3One6gLDTwYAtzM4PMetQBB2i8xtI860ef0JhYtfH7Aco9nEMtrAJcvZhm1-jl063Gd78nifo89XH9eV1ufy0uLk8X5aGYcJKB6ClYNpZ4zQzDAjbGMpNRdyGYOB1bTEYR_jGWnCOMS5dBdRybQlm1tET9P5wt0_xfoQ8qM5nA22rA8QxK8KobOqKyur_lHJRC0GpmOi7Z_QujilMj0yqElTWkjWTOj0ok2LOCZzqk-90elAEq8cq1FSFeqpisvOD3fsWHv4N1flq9SdRHhI-D_Djb0Knb4o3tKnVl9uFqpZfV1fNxVp9oL8A7lyboA</recordid><startdate>20130715</startdate><enddate>20130715</enddate><creator>Nawalakhe, Rupesh</creator><creator>Shi, Quan</creator><creator>Vitchuli, Narendiran</creator><creator>Noar, Jesse</creator><creator>Caldwell, Jane M.</creator><creator>Breidt, Frederick</creator><creator>Bourham, Mohamed A.</creator><creator>Zhang, Xiangwu</creator><creator>McCord, Marian G.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><general>Wiley Subscription Services, Inc</general><scope>BSCLL</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SR</scope><scope>8FD</scope><scope>JG9</scope><scope>7S9</scope><scope>L.6</scope></search><sort><creationdate>20130715</creationdate><title>Novel atmospheric plasma enhanced chitosan nanofiber/gauze composite wound dressings</title><author>Nawalakhe, Rupesh ; Shi, Quan ; Vitchuli, Narendiran ; Noar, Jesse ; Caldwell, Jane M. ; Breidt, Frederick ; Bourham, Mohamed A. ; Zhang, Xiangwu ; McCord, Marian G.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4014-feea984afdcfa4c4e14bc36c21fb10e655d0ecf16bddeff4469f2e3d6ad104df3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>absorbance</topic><topic>active sites</topic><topic>adhesion</topic><topic>air</topic><topic>antimicrobial properties</topic><topic>Atmospherics</topic><topic>bandages</topic><topic>biomedical applications</topic><topic>biopolymers and renewable polymers</topic><topic>carbon</topic><topic>Chitosan</topic><topic>composite materials</topic><topic>composites</topic><topic>cotton</topic><topic>durability</topic><topic>Electrospinning</topic><topic>fabrics</topic><topic>Gauze</topic><topic>Materials science</topic><topic>Nanocomposites</topic><topic>nanofibers</topic><topic>Nanomaterials</topic><topic>Nanostructure</topic><topic>nanostructured polymers</topic><topic>organofluorine compounds</topic><topic>oxygen</topic><topic>permeability</topic><topic>Polymers</topic><topic>tissue repair</topic><topic>vapors</topic><topic>X-ray photoelectron spectroscopy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nawalakhe, Rupesh</creatorcontrib><creatorcontrib>Shi, Quan</creatorcontrib><creatorcontrib>Vitchuli, Narendiran</creatorcontrib><creatorcontrib>Noar, Jesse</creatorcontrib><creatorcontrib>Caldwell, Jane M.</creatorcontrib><creatorcontrib>Breidt, Frederick</creatorcontrib><creatorcontrib>Bourham, Mohamed A.</creatorcontrib><creatorcontrib>Zhang, Xiangwu</creatorcontrib><creatorcontrib>McCord, Marian G.</creatorcontrib><collection>Istex</collection><collection>CrossRef</collection><collection>Engineered Materials Abstracts</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><collection>AGRICOLA</collection><collection>AGRICOLA - Academic</collection><jtitle>Journal of applied polymer science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nawalakhe, Rupesh</au><au>Shi, Quan</au><au>Vitchuli, Narendiran</au><au>Noar, Jesse</au><au>Caldwell, Jane M.</au><au>Breidt, Frederick</au><au>Bourham, Mohamed A.</au><au>Zhang, Xiangwu</au><au>McCord, Marian G.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Novel atmospheric plasma enhanced chitosan nanofiber/gauze composite wound dressings</atitle><jtitle>Journal of applied polymer science</jtitle><addtitle>J. Appl. Polym. Sci</addtitle><date>2013-07-15</date><risdate>2013</risdate><volume>129</volume><issue>2</issue><spage>916</spage><epage>923</epage><pages>916-923</pages><issn>0021-8995</issn><issn>1097-4628</issn><eissn>1097-4628</eissn><coden>JAPNAB</coden><abstract>Electrospun chitosan nanofibers were deposited onto atmospheric plasma treated cotton gauze to create a novel composite bandage with higher adhesion, better handling properties, enhanced bioactivity, and moisture management. Plasma treatment of the gauze substrate was performed to improve the durability of the nanofiber/gauze interface. The chitosan nanofibers were electrospun at 3–7% concentration in trifluoroacetic acid. The composite bandages were analyzed using peel, gelbo flex, antimicrobial assay, moisture vapor transmission rate, X‐ray photoelectron spectroscopy (XPS), absorbency, and air permeability tests. The peel test showed that plasma treatment of the substrate increased the adhesion between nanofiber layers and gauze substrate by up to four times. Atmospheric plasma pretreatment of the gauze fabric prior to electrospinning significantly reduced degradation of the nanofiber layer due to repetitive flexing. The chitosan nanofiber layer contributes significantly to the antimicrobial properties of the bandage. Air permeability and moisture vapor transport were reduced due to the presence of a nanofiber layer upon the substrate. XPS of the plasma treated cotton substrate showed formation of active sites on the surface, decrease in carbon content, and increase in oxygen content as compared to the untreated gauze. Deposition of chitosan nanofibers also increased the absorbency of gauze substrate. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013</abstract><cop>Hoboken</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><doi>10.1002/app.38804</doi><tpages>8</tpages></addata></record> |
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| ispartof | Journal of applied polymer science, 2013-07, Vol.129 (2), p.916-923 |
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| source | Wiley Online Library Journals Frontfile Complete |
| subjects | absorbance active sites adhesion air antimicrobial properties Atmospherics bandages biomedical applications biopolymers and renewable polymers carbon Chitosan composite materials composites cotton durability Electrospinning fabrics Gauze Materials science Nanocomposites nanofibers Nanomaterials Nanostructure nanostructured polymers organofluorine compounds oxygen permeability Polymers tissue repair vapors X-ray photoelectron spectroscopy |
| title | Novel atmospheric plasma enhanced chitosan nanofiber/gauze composite wound dressings |
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