Squaramide-catalysed enantionselective Mannich reaction of imines bearing a heterocycle with malonates

An efficient enantioselective Mannich reaction of imines bearing a heterocycle with malonates catalysed by a cinchona-based squaramide organocatalyst has been developed. This catalytic asymmetric reaction afforded the beta -amino ester derivatives containing a heterocycle moiety in high yields (up t...

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Veröffentlicht in:	RSC advances 2013-01, Vol.3 (37), p.16349-16358
Hauptverfasser:	He, Hai-Xiao, Du, Da-Ming
Format:	Artikel
Sprache:	eng
Schlagworte:	Asymmetry Bearing Cases (containers) Catalysis Catalysts Derivatives Esters Imines
Online-Zugang:	Volltext
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