Viscoelastic properties of poly(ε-caprolactone) - hydroxyapatite micro- and nano-composites
Various composites have been proposed in the literature for the fabrication of bioscaffolds for bone tissue engineering. These materials include poly(ε‐caprolactone) (PCL) with hydroxyapatite (HA). Since the biomaterial acts as the medium that transfers mechanical signals from the body to the cells,...
Gespeichert in:
| Veröffentlicht in: | Polymers for advanced technologies 2013-02, Vol.24 (2), p.144-150 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 150 |
|---|---|
| container_issue | 2 |
| container_start_page | 144 |
| container_title | Polymers for advanced technologies |
| container_volume | 24 |
| creator | Leung, Linus H. Naguib, Hani E. |
| description | Various composites have been proposed in the literature for the fabrication of bioscaffolds for bone tissue engineering. These materials include poly(ε‐caprolactone) (PCL) with hydroxyapatite (HA). Since the biomaterial acts as the medium that transfers mechanical signals from the body to the cells, the fundamental properties of the biomaterials should be characterized. Furthermore, in order to control the processing of these materials into scaffolds, the characterization of the fundamental properties is also necessary. In this study, the physical, thermal, mechanical, and viscoelastic properties of the PCL‐HA micro‐ and nano‐composites were characterized. Although the addition of filler particles increased the compressive modulus by up to 450%, the thermal and viscoelastic properties were unaffected. Furthermore, although the presence of water plasticized the polymer, the viscoelastic behavior was only minimally affected. Testing the composites under various conditions showed that the addition of HA can strengthen PCL without changing its viscoelastic response. The results found in this study can be used to further understand and approximate the time‐dependent behavior of scaffolds for bone tissue engineering. Copyright © 2012 John Wiley & Sons, Ltd. |
| doi_str_mv | 10.1002/pat.3061 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1439735990</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1439735990</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4311-a2ffa955fa29471094d76f150883d308a6b4056906653889159ea54842be915d3</originalsourceid><addsrcrecordid>eNp1kNlKxDAUhosouIKPUBBBL6JZm-ZSxBVxgdG5EcIxTTHaaWrSwemD-Ro-kxkcFARzk-V8fPnPybJtgg8IxvSwg_6A4YIsZWsEK4WIKMny_MwpkoTL1Ww9xheMU03JtezxwUXjbQOxdybvgu9s6J2Nua_zzjfD3ucHMpDeGzC9b-1-jvLnoQp-NkD6yvU2nzgTPMqhrfIWWo-Mn3Q-pkrczFZqaKLdWuwb2f3pyej4HF3dnF0cH10hwxkhCGhdgxKiBqq4TKl5JYuaCFyWrGK4hOKJY1EoXBSClaUiQlkQvOT0yaZLxTayvW9vyvk2tbHXk9SVbRporZ9GTThTkgmlcEJ3_qAvfhralE4TKmlahIlfYeosxmBr3QU3gTBogvV8zDr1rudjTujuQgjRQFMHaI2LPzyVRHAq5kr0zb27xg7_-vTt0WjhXfAu9nb2w0N41YVkUujx9Zk-H8u7UXnJNWNftHyZLw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1272222135</pqid></control><display><type>article</type><title>Viscoelastic properties of poly(ε-caprolactone) - hydroxyapatite micro- and nano-composites</title><source>Wiley Online Library Journals Frontfile Complete</source><creator>Leung, Linus H. ; Naguib, Hani E.</creator><creatorcontrib>Leung, Linus H. ; Naguib, Hani E.</creatorcontrib><description>Various composites have been proposed in the literature for the fabrication of bioscaffolds for bone tissue engineering. These materials include poly(ε‐caprolactone) (PCL) with hydroxyapatite (HA). Since the biomaterial acts as the medium that transfers mechanical signals from the body to the cells, the fundamental properties of the biomaterials should be characterized. Furthermore, in order to control the processing of these materials into scaffolds, the characterization of the fundamental properties is also necessary. In this study, the physical, thermal, mechanical, and viscoelastic properties of the PCL‐HA micro‐ and nano‐composites were characterized. Although the addition of filler particles increased the compressive modulus by up to 450%, the thermal and viscoelastic properties were unaffected. Furthermore, although the presence of water plasticized the polymer, the viscoelastic behavior was only minimally affected. Testing the composites under various conditions showed that the addition of HA can strengthen PCL without changing its viscoelastic response. The results found in this study can be used to further understand and approximate the time‐dependent behavior of scaffolds for bone tissue engineering. Copyright © 2012 John Wiley & Sons, Ltd.</description><identifier>ISSN: 1042-7147</identifier><identifier>EISSN: 1099-1581</identifier><identifier>DOI: 10.1002/pat.3061</identifier><identifier>CODEN: PADTE5</identifier><language>eng</language><publisher>Chichester: Blackwell Publishing Ltd</publisher><subject>Applied sciences ; Biological and medical sciences ; biomaterials ; Biomedical materials ; Bones ; Composites ; Controllers ; Exact sciences and technology ; Forms of application and semi-finished materials ; Hydroxyapatite ; Medical sciences ; nano-composites ; Nanomaterials ; Nanostructure ; poly(ε-caprolactone) ; Polymer industry, paints, wood ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Surgical implants ; Technology of polymers ; Technology. Biomaterials. Equipments ; Viscoelasticity</subject><ispartof>Polymers for advanced technologies, 2013-02, Vol.24 (2), p.144-150</ispartof><rights>Copyright © 2012 John Wiley & Sons, Ltd.</rights><rights>2014 INIST-CNRS</rights><rights>Copyright © 2013 John Wiley & Sons, Ltd.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4311-a2ffa955fa29471094d76f150883d308a6b4056906653889159ea54842be915d3</citedby><cites>FETCH-LOGICAL-c4311-a2ffa955fa29471094d76f150883d308a6b4056906653889159ea54842be915d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fpat.3061$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fpat.3061$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27923,27924,45573,45574</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=27154255$$DView record in Pascal Francis$$Hfree_for_read</backlink></links><search><creatorcontrib>Leung, Linus H.</creatorcontrib><creatorcontrib>Naguib, Hani E.</creatorcontrib><title>Viscoelastic properties of poly(ε-caprolactone) - hydroxyapatite micro- and nano-composites</title><title>Polymers for advanced technologies</title><addtitle>Polym. Adv. Technol</addtitle><description>Various composites have been proposed in the literature for the fabrication of bioscaffolds for bone tissue engineering. These materials include poly(ε‐caprolactone) (PCL) with hydroxyapatite (HA). Since the biomaterial acts as the medium that transfers mechanical signals from the body to the cells, the fundamental properties of the biomaterials should be characterized. Furthermore, in order to control the processing of these materials into scaffolds, the characterization of the fundamental properties is also necessary. In this study, the physical, thermal, mechanical, and viscoelastic properties of the PCL‐HA micro‐ and nano‐composites were characterized. Although the addition of filler particles increased the compressive modulus by up to 450%, the thermal and viscoelastic properties were unaffected. Furthermore, although the presence of water plasticized the polymer, the viscoelastic behavior was only minimally affected. Testing the composites under various conditions showed that the addition of HA can strengthen PCL without changing its viscoelastic response. The results found in this study can be used to further understand and approximate the time‐dependent behavior of scaffolds for bone tissue engineering. Copyright © 2012 John Wiley & Sons, Ltd.</description><subject>Applied sciences</subject><subject>Biological and medical sciences</subject><subject>biomaterials</subject><subject>Biomedical materials</subject><subject>Bones</subject><subject>Composites</subject><subject>Controllers</subject><subject>Exact sciences and technology</subject><subject>Forms of application and semi-finished materials</subject><subject>Hydroxyapatite</subject><subject>Medical sciences</subject><subject>nano-composites</subject><subject>Nanomaterials</subject><subject>Nanostructure</subject><subject>poly(ε-caprolactone)</subject><subject>Polymer industry, paints, wood</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Surgical implants</subject><subject>Technology of polymers</subject><subject>Technology. Biomaterials. Equipments</subject><subject>Viscoelasticity</subject><issn>1042-7147</issn><issn>1099-1581</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><recordid>eNp1kNlKxDAUhosouIKPUBBBL6JZm-ZSxBVxgdG5EcIxTTHaaWrSwemD-Ro-kxkcFARzk-V8fPnPybJtgg8IxvSwg_6A4YIsZWsEK4WIKMny_MwpkoTL1Ww9xheMU03JtezxwUXjbQOxdybvgu9s6J2Nua_zzjfD3ucHMpDeGzC9b-1-jvLnoQp-NkD6yvU2nzgTPMqhrfIWWo-Mn3Q-pkrczFZqaKLdWuwb2f3pyej4HF3dnF0cH10hwxkhCGhdgxKiBqq4TKl5JYuaCFyWrGK4hOKJY1EoXBSClaUiQlkQvOT0yaZLxTayvW9vyvk2tbHXk9SVbRporZ9GTThTkgmlcEJ3_qAvfhralE4TKmlahIlfYeosxmBr3QU3gTBogvV8zDr1rudjTujuQgjRQFMHaI2LPzyVRHAq5kr0zb27xg7_-vTt0WjhXfAu9nb2w0N41YVkUujx9Zk-H8u7UXnJNWNftHyZLw</recordid><startdate>201302</startdate><enddate>201302</enddate><creator>Leung, Linus H.</creator><creator>Naguib, Hani E.</creator><general>Blackwell Publishing Ltd</general><general>Wiley</general><general>Wiley Subscription Services, Inc</general><scope>BSCLL</scope><scope>IQODW</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SR</scope><scope>8FD</scope><scope>JG9</scope><scope>7U5</scope><scope>L7M</scope></search><sort><creationdate>201302</creationdate><title>Viscoelastic properties of poly(ε-caprolactone) - hydroxyapatite micro- and nano-composites</title><author>Leung, Linus H. ; Naguib, Hani E.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4311-a2ffa955fa29471094d76f150883d308a6b4056906653889159ea54842be915d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Applied sciences</topic><topic>Biological and medical sciences</topic><topic>biomaterials</topic><topic>Biomedical materials</topic><topic>Bones</topic><topic>Composites</topic><topic>Controllers</topic><topic>Exact sciences and technology</topic><topic>Forms of application and semi-finished materials</topic><topic>Hydroxyapatite</topic><topic>Medical sciences</topic><topic>nano-composites</topic><topic>Nanomaterials</topic><topic>Nanostructure</topic><topic>poly(ε-caprolactone)</topic><topic>Polymer industry, paints, wood</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Surgical implants</topic><topic>Technology of polymers</topic><topic>Technology. Biomaterials. Equipments</topic><topic>Viscoelasticity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Leung, Linus H.</creatorcontrib><creatorcontrib>Naguib, Hani E.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>CrossRef</collection><collection>Engineered Materials Abstracts</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Advanced Technologies Database with Aerospace</collection><jtitle>Polymers for advanced technologies</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Leung, Linus H.</au><au>Naguib, Hani E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Viscoelastic properties of poly(ε-caprolactone) - hydroxyapatite micro- and nano-composites</atitle><jtitle>Polymers for advanced technologies</jtitle><addtitle>Polym. Adv. Technol</addtitle><date>2013-02</date><risdate>2013</risdate><volume>24</volume><issue>2</issue><spage>144</spage><epage>150</epage><pages>144-150</pages><issn>1042-7147</issn><eissn>1099-1581</eissn><coden>PADTE5</coden><abstract>Various composites have been proposed in the literature for the fabrication of bioscaffolds for bone tissue engineering. These materials include poly(ε‐caprolactone) (PCL) with hydroxyapatite (HA). Since the biomaterial acts as the medium that transfers mechanical signals from the body to the cells, the fundamental properties of the biomaterials should be characterized. Furthermore, in order to control the processing of these materials into scaffolds, the characterization of the fundamental properties is also necessary. In this study, the physical, thermal, mechanical, and viscoelastic properties of the PCL‐HA micro‐ and nano‐composites were characterized. Although the addition of filler particles increased the compressive modulus by up to 450%, the thermal and viscoelastic properties were unaffected. Furthermore, although the presence of water plasticized the polymer, the viscoelastic behavior was only minimally affected. Testing the composites under various conditions showed that the addition of HA can strengthen PCL without changing its viscoelastic response. The results found in this study can be used to further understand and approximate the time‐dependent behavior of scaffolds for bone tissue engineering. Copyright © 2012 John Wiley & Sons, Ltd.</abstract><cop>Chichester</cop><pub>Blackwell Publishing Ltd</pub><doi>10.1002/pat.3061</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1042-7147 |
| ispartof | Polymers for advanced technologies, 2013-02, Vol.24 (2), p.144-150 |
| issn | 1042-7147 1099-1581 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1439735990 |
| source | Wiley Online Library Journals Frontfile Complete |
| subjects | Applied sciences Biological and medical sciences biomaterials Biomedical materials Bones Composites Controllers Exact sciences and technology Forms of application and semi-finished materials Hydroxyapatite Medical sciences nano-composites Nanomaterials Nanostructure poly(ε-caprolactone) Polymer industry, paints, wood Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgical implants Technology of polymers Technology. Biomaterials. Equipments Viscoelasticity |
| title | Viscoelastic properties of poly(ε-caprolactone) - hydroxyapatite micro- and nano-composites |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T23%3A13%3A33IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Viscoelastic%20properties%20of%20poly(%CE%B5-caprolactone)%20-%20hydroxyapatite%20micro-%20and%20nano-composites&rft.jtitle=Polymers%20for%20advanced%20technologies&rft.au=Leung,%20Linus%20H.&rft.date=2013-02&rft.volume=24&rft.issue=2&rft.spage=144&rft.epage=150&rft.pages=144-150&rft.issn=1042-7147&rft.eissn=1099-1581&rft.coden=PADTE5&rft_id=info:doi/10.1002/pat.3061&rft_dat=%3Cproquest_cross%3E1439735990%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1272222135&rft_id=info:pmid/&rfr_iscdi=true |