Effects of calcium channel blocking agents on membrane microviscosity and calcium in the liver of the carbon tetrachloride treated rat

Membrane microviscosity was determined from the polarized fluorescence of diphenylhexatriene in plasma membranes and microsomes prepared from the liver of carbon tetrachloride treated rats. It was greatly depressed between 12 and 24 hr after the administration of the carbon tetrachloride. Depression...

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Veröffentlicht in:	Biochemical pharmacology 1984-11, Vol.33 (22), p.3553-3560
Hauptverfasser:	Landon, Erwin J., Jaiswal, Rama k., Naukam, Rebecca J., Sastry, B.V.Rama
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Calcium - metabolism calcium antagonists Calcium Channel Blockers - pharmacology carbon tetrachloride Carbon Tetrachloride Poisoning - metabolism Cell Membrane - drug effects Cell Membrane - metabolism Cell Membrane - ultrastructure Chemical and industrial products toxicology. Toxic occupational diseases Chlorpromazine - pharmacology Kinetics Liposomes liver Liver - drug effects Liver - metabolism Male Medical sciences membrane fluidity Membrane Lipids - metabolism Microsomes, Liver - drug effects Microsomes, Liver - metabolism Nifedipine - pharmacology Rats Rats, Inbred Strains Solvents Toxicology Verapamil - pharmacology Viscosity
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