Abnormal development of NG2 super(+)PDGFR- alpha super(+) neural progenitor cells leads to neonatal hydrocephalus in a ciliopathy mouse model

Hydrocephalus is a common neurological disorder that leads to expansion of the cerebral ventricles and is associated with a high rate of morbidity and mortality. Most neonatal cases are of unknown etiology and are likely to have complex inheritance involving multiple genes and environmental factors....

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Veröffentlicht in:Nature medicine 2012-12, Vol.18 (12), p.1797-1804
Hauptverfasser: Carter, Calvin S, Vogel, Timothy W, Zhang, Qihong, Seo, Seongjin, Swiderski, Ruth E, Moninger, Thomas O, Cassell, Martin D, Thedens, Daniel R, Keppler-Noreuil, Kim M, Nopoulos, Peggy, Nishimura, Darryl Y, Searby, Charles C, Bugge, Kevin, Sheffield, Val C
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Sprache:eng
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