Propolis alleviates 2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced histological changes, oxidative stress and DNA damage in rat liver

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces hepatic damage. Propolis exhibits antioxidant properties and several studies suggest that supplementations with antioxidants can influence hepatotoxicity. Therefore, the aim of the current study was to explore the effectiveness of propolis in allevi...

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Veröffentlicht in:	Toxicology and industrial health 2013-09, Vol.29 (8), p.677-685
Hauptverfasser:	Türkez, Hasan, Geyikoğlu, Fatime, Yousef, Mokhtar I, Toğar, Basak, Vançelik, Serhat
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants Antioxidants - pharmacology Biology Chemical and Drug Induced Liver Injury - drug therapy Dioxins DNA damage DNA Damage - drug effects Dose-Response Relationship, Drug Drug dosages Enzymes Flavonoids Free radicals Hepatocytes - drug effects Histopathology Laboratory animals Liver Liver - drug effects Liver - pathology Male Oxidative stress Oxidative Stress - drug effects Polychlorinated Dibenzodioxins - toxicity Propolis - pharmacology Rats Rats, Sprague-Dawley Toxicity Toxicology
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