Inside Cover: Artemisinin-Polypyrrole Conjugates: Synthesis, DNA Binding Studies and Preliminary Antiproliferative Evaluation (ChemMedChem 5/2013)

Greater than the sum of its parts: Artemisinins are currently in phaseI-II clinical trials against breast, colorectal and non-small-cell lung cancers. In an attempt to offer increased specificity, a series of hybrid artemisinin-polypyrrole minor groove binder conjugates are described. DNA binding/mo...

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Veröffentlicht in:	ChemMedChem 2013-05, Vol.8 (5), p.674-674
Hauptverfasser:	La Pensée, Louise, Sabbani, Sunil, Sharma, Raman, Bhamra, Inder, Shore, Emma, Chadwick, Amy E., Berry, Neil G., Firman, James, Araujo, Nuna C., Cabral, Lília, Cristiano, Maria L. S., Bateman, Cerys, Janneh, Omar, Gavrila, Adelina, Wu, Yi Hang, Hussain, Afthab, Ward, Stephen A., Stocks, Paul A., Cosstick, Rick, O'Neill, Paul M.
Format:	Artikel
Sprache:	eng
Schlagworte:	artemisinin binding studies cytotoxicity DNA Indexing in process molecular modelling
Online-Zugang:	Volltext
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