Multiple Sclerosis: Modulation of Toll-Like Receptor (TLR) Expression by Interferon- beta Includes Upregulation of TLR7 in Plasmacytoid Dendritic Cells. e70626

Interferon- beta is an established treatment for patients with multiple sclerosis (MS) but its mechanisms of action are not well understood. Viral infections are a known trigger of MS relapses. Toll-like receptors (TLRs) are key components of the innate immune system, which sense conserved structure...

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Veröffentlicht in:PloS one 2013-08, Vol.8 (8)
Hauptverfasser: Derkow, Katja, Bauer, Jakob MJ, Hecker, Michael, Paap, Brigitte K, Thamilarasan, Madhan, Koczan, Dirk, Schott, Eckart, Deuschle, Katrin, Bellmann-Strobl, Judith, Paul, Friedemann
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Sprache:eng
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