Lab-on-Chip: Acute On-Chip HIV Detection Through Label-Free Electrical Sensing of Viral Nano-Lysate (Small 15/2013)

, U. Demirci and co-workers address the need for clinical HIV-I detection at the acute stage, where antibodies are present in very low concentrations. Their fast and extremely affordable portable diagnostic tool allows on-chip virus detection without the need for any labeling steps. Through impedanc...

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Veröffentlicht in:Small (Weinheim an der Bergstrasse, Germany) Germany), 2013-08, Vol.9 (15), p.2478-2478
Hauptverfasser: Shafiee, Hadi, Jahangir, Muntasir, Inci, Fatih, Wang, ShuQi, Willenbrecht, Remington B. M., Giguel, Francoise F., Tsibris, Athe M. N., Kuritzkes, Daniel R., Demirci, Utkan
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container_end_page 2478
container_issue 15
container_start_page 2478
container_title Small (Weinheim an der Bergstrasse, Germany)
container_volume 9
creator Shafiee, Hadi
Jahangir, Muntasir
Inci, Fatih
Wang, ShuQi
Willenbrecht, Remington B. M.
Giguel, Francoise F.
Tsibris, Athe M. N.
Kuritzkes, Daniel R.
Demirci, Utkan
description , U. Demirci and co-workers address the need for clinical HIV-I detection at the acute stage, where antibodies are present in very low concentrations. Their fast and extremely affordable portable diagnostic tool allows on-chip virus detection without the need for any labeling steps. Through impedance analysis, the device can sense the unique electrical signature of the viral nano-lysates. This means that the tool is also highly selective, could be easily extended for use in detecting other infectious diseases, and could even be adapted to detect multiple diseases at the same time.
doi_str_mv 10.1002/smll.201370085
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source Wiley Online Library - AutoHoldings Journals
subjects Human immunodeficiency virus
impedance spectroscopy
lab-on-chip
pathogen detection
point-of-care diagnosis
virus lysis
title Lab-on-Chip: Acute On-Chip HIV Detection Through Label-Free Electrical Sensing of Viral Nano-Lysate (Small 15/2013)
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