Decreased circulating large granular lymphocytes associated with depressed natural killer cell activity in renal transplant recipients

Renal transplant recipients (RTR) receiving prednisone and azathioprine (AZ) frequently have depressed natural killer (NK) cell activity. In humans, NK activity is mediated by the large granular lymphocyte (LGL). To determine the mechanism of depressed NK activity among RTR, we quantitated the NK ac...

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Veröffentlicht in:	Transplantation 1984-10, Vol.38 (4), p.351-356
Hauptverfasser:	Ramsey, K M, Djeu, J Y, Rook, A H
Format:	Artikel
Sprache:	eng
Schlagworte:	Azathioprine - therapeutic use Cytotoxicity Tests, Immunologic Cytotoxicity, Immunologic - drug effects Female Humans Immunosuppressive Agents - therapeutic use Interferon Type I - pharmacology Kidney Transplantation Killer Cells, Natural - classification Killer Cells, Natural - immunology Leukocyte Count Male Prednisone - therapeutic use
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